SUN-1334H free base
SUN-1334H free base is an orally active inhibitor for histamine H1 receptor, with an IC50 of 20.3 nM and Ki of 9.7 nM. SUN-1334H free base inhibits histamine-induced contractions of isolated guinea-pig ileum with an IC50 of 0.198 μM. SUN-1334H free base inhibits histamine-induced bronchoconstriction in guinea pigs, histamine-induced skin wheals in beagle dogs, and ovalbumin-induced rhinitis in guinea pigs.
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- CAS No.: 607737-00-8
- Formule: C23H26F2N2O3
- Masse moléculaire:416.46
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
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Activité biologique
Description
IC50 & Target
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H1 Receptor 20.3 nM (IC50) |
Dopamine D3 receptor 3.43 μM (IC50) |
σ1 5.46 μM (IC50) |
Alpha-1D adrenergic receptor 7.76 μM (IC50) |
Chemical Information
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CAS No. 607737-00-8
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Masse moléculaire 416.46
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Formule C23H26F2N2O3
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SMILES
OC(COC/C=C/CN(CC1)CCN1C(C2=CC=C(C=C2)F)C3=CC=C(C=C3)F)=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
SUN-1334H free base Related Classifications
HY-164010 Related Classifications
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