SC-50605
SC-50605 and SC-51146 are second-generation leukotriene B4 (LTB4) receptor antagonists that effectively inhibit LTB4-induced chemotaxis in guinea pigs. SC-50605 targets the LTB4 receptor and has the potential to inhibit inflammatory diseases such as asthma, rheumatoid arthritis, and skin diseases..
For research use only. We do not sell to patients.
- CAS No.: 138828-39-4
- Formula: C30H35NO6S
- Molecular Weight:537.67
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
All Leukotriene Receptor Isoforms
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Biological Activity
LTB4[1]
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HL-60 | IC50 |
660 nM
Compound: 35
|
Inhibitory activity against LTB4 production in HL60s.
Inhibitory activity against LTB4 production in HL60s.
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[PMID: 7699700] |
| HL-60 | IC50 |
928 nM
Compound: 35
|
Inhibitory activity against PGE-2 production in HL60s.
Inhibitory activity against PGE-2 production in HL60s.
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[PMID: 7699700] |
Chemical Information
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CAS No. 138828-39-4
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Molecular Weight 537.67
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Formula C30H35NO6S
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SMILES
O=C(O)C1CCC2=CC=C(C(CCC)=C2O1)OCCCOC3=CC=C(C(OC)=C3CC4CC4)C5=CSC=N5
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Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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