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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
4 Results for "
procaspase-8
" in MedChemExpress (MCE) Product Catalog:
Products (4)
4 Results for "procaspase-8" in MCE Product Catalog:
9
9 Cited Publications
Synonyms: RGDS peptide; Fibronectin tetrapeptide
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Cat. No.: HY-12290A
Synonyms: RGDS peptide TFA; Fibronectin tetrapeptide TFA
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Cat. No.: HY-12290R
CAS No.: 91037-65-9
Synonyms: RGDS peptide (Standard); Fibronectin tetrapeptide (Standard)
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Cat. No.: HY-182307
CAS No.: 1018153-87-1
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OH14 is a cellular FLICE-like inhibitory protein (cFLIP) inhibitor and TNF-related apoptosis-inducing ligand (TRAIL) sensitizer. OH14 selectively binds to the DED1 pocket of cFLIP, disrupting its recruitment to the TRAIL-death inducing signalling complex without affecting procaspase-8 recruitment to FADD, allowing procaspase-8 activation. OH14 promotes TRAIL-mediated apoptosis and impairs cell viability in breast cancer systems when combined with TRAIL. OH14 can be used for the research of breast cancer .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
