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Results for "

purgative

" in MedChemExpress (MCE) Product Catalog:

8

Inhibitors & Agonists

8

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N2229
    Rhapontigenin
    3 Publications Verification

    		 Cytochrome P450 Fungal Bacterial Infection Inflammation/Immunology Cancer
    Rhapontigenin is a natural analog of resveratrol with anticancer, antioxidant, antifungal and antibacterial activities. Rhapontigenin is amechanism-based, potent and selective cytochrome P450 1A1 inactivator (IC50  = 400 nM). Rhapontigenin exhibits 400-fold and 23-fold selectivity for P450 1A1 over P450 1A2 and P450 1B1, respectively .
    Rhapontigenin
  • HY-N1972
    Sennoside C

    		Others Neurological Disease Metabolic Disease
    Sennoside C is an orally active component of the traditional Chinese medicine Sennae Folium. Sennoside C can bind to human lysozyme and inhibit its amyloid fibrosis (IC50: 186.20 μM). Sennoside C has certain purgative activity. Sennoside C can be used in the research of diarrhea and anti-amyloid related diseases .
    Sennoside C
  • HY-N6082
    Rhein 8-O-β-D-Glucopyranoside
    1 Publications Verification

    		 Apoptosis Bcl-2 Family Caspase TGF-beta/Smad Bacterial Infection Metabolic Disease Inflammation/Immunology
    Rhein 8-O-β-D-Glucopyranoside is an orally active glycoside found in Rhubarb. Rhein 8-O-β-D-Glucopyranoside attenuates high glucose-induced apoptosis, recovers altered lincRNA ANRIL and let-7a expression, reverses high glucose-altered Bcl-2 and cleaved caspase-3 protein expression, and inhibits TGF-β1/Smad signaling. Rhein 8-O-β-D-Glucopyranoside accelerates Sennoside A (HY-N0365) metabolism, stimulates sennoside A purgative activity. Rhein 8-O-β-D-Glucopyranoside inhibits bacterial biofilm formation, suppresses its virulence gene expression, and exerts antibacterial activity. Rhein 8-O-β-D-Glucopyranoside can be used for the research of diabetic nephropathy, constipation, and infection .
    Rhein 8-O-β-D-Glucopyranoside
  • HY-N1503
    Methyl deacetylasperulosidate

    6α-Hydroxygeniposide; Deacetylasperulosidic acid methyl ester

    		 Others Metabolic Disease
    Methyl deacetylasperulosidate is an iridoid and shows purgative effects in mice and lowers the blood glucose level in normal mice .
    Methyl deacetylasperulosidate
  • HY-N1503R
    Methyl deacetylasperulosidate (Standard)

    6α-Hydroxygeniposide (Standard); Deacetylasperulosidic acid methyl ester (Standard)

    		 Reference Standards Others Metabolic Disease
    Methyl deacetylasperulosidate (Standard) is the analytical standard of Methyl deacetylasperulosidate. This product is intended for research and analytical applications. Methyl deacetylasperulosidate is an iridoid and shows purgative effects in mice and lowers the blood glucose level in normal mice .
    Methyl deacetylasperulosidate (Standard)
  • HY-N2229R
    Rhapontigenin (Standard)

    		Reference Standards Cytochrome P450 Fungal Bacterial Infection Inflammation/Immunology Cancer
    Rhapontigenin (Standard) is the analytical standard of Rhapontigenin. This product is intended for research and analytical applications. Rhapontigenin is a natural analog of resveratrol with anticancer, antioxidant, antifungal and antibacterial activities. Rhapontigenin is amechanism-based, potent and selective cytochrome P450 1A1 inactivator (IC50 = 400 nM). Rhapontigenin exhibits 400-fold and 23-fold selectivity for P450 1A1 over P450 1A2 and P450 1B1, respectively .
    Rhapontigenin (Standard)
  • HY-N1972R
    Sennoside C (Standard)

    		Reference Standards Others Neurological Disease Metabolic Disease
    Sennoside C (Standard) is the analytical standard of Sennoside C (HY-N1972). This product is intended for research and analytical applications. Sennoside C is an orally active component of the traditional Chinese medicine Sennae Folium. Sennoside C can bind to human lysozyme and inhibit its amyloid fibrosis (IC50: 186.20 μM). Sennoside C has certain purgative activity. Sennoside C can be used in the research of diarrhea and anti-amyloid related diseases .
    Sennoside C (Standard)
  • HY-N6082R
    Rhein 8-O-β-D-Glucopyranoside (Standard)

    		Reference Standards Apoptosis Bacterial Bcl-2 Family Caspase TGF-beta/Smad Infection Metabolic Disease Inflammation/Immunology
    Rhein 8-O-β-D-Glucopyranoside (Standard) is the analytical standard of Rhein 8-O-β-D-Glucopyranoside (HY-N6083). This product is intended for research and analytical applications. Rhein 8-O-β-D-Glucopyranoside is an orally active glycoside found in Rhubarb. Rhein 8-O-β-D-Glucopyranoside attenuates high glucose-induced apoptosis, recovers altered lincRNA ANRIL and let-7a expression, reverses high glucose-altered Bcl-2 and cleaved caspase-3 protein expression, and inhibits TGF-β1/Smad signaling. Rhein 8-O-β-D-Glucopyranoside accelerates Sennoside A (HY-N0365) metabolism, stimulates sennoside A purgative activity. Rhein 8-O-β-D-Glucopyranoside inhibits bacterial biofilm formation, suppresses its virulence gene expression, and exerts antibacterial activity. Rhein 8-O-β-D-Glucopyranoside can be used for the research of diabetic nephropathy, constipation, and infection .
    Rhein 8-O-β-D-Glucopyranoside (Standard)

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