5 Results for "

purgative

" in MedChemExpress (MCE) Product Catalog:
Products (5)

5 Results for "purgative" in MCE Product Catalog:

1
Sennoside C
Sennoside C
0 Images
1 Cited Publications
Cat. No.: HY-N1972
CAS No.: 37271-16-2
Category:  

Quinones Anthraquinones Other Diseases Phenols Polyphenols Leguminosae Extract Plants Cassia angustifolia Disease Research Fields

Target:  

Others

Sennoside C is an orally active component of the traditional Chinese medicine Sennae Folium. Sennoside C can bind to human lysozyme and inhibit its amyloid fibrosis (IC50: 186.20 μM). Sennoside C has certain purgative activity. Sennoside C can be used in the research of diarrhea and anti-amyloid related diseases .
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1
Rhein 8-O-β-D-Glucopyranoside
Rhein 8-O-β-D-Glucopyranoside
0 Images
1 Cited Publications
Cat. No.: HY-N6082
CAS No.: 34298-86-7
Category:  

Quinones Monophenols Rheum palmatum L. Anthraquinones Metabolic Disease Phenols Plants Disease Research Fields Polygonaceae Extract

Target:  

Apoptosis Bcl-2 Family Caspase TGF-beta/Smad Bacterial

Rhein 8-O-β-D-Glucopyranoside is an orally active glycoside found in Rhubarb. Rhein 8-O-β-D-Glucopyranoside attenuates high glucose-induced apoptosis, recovers altered lincRNA ANRIL and let-7a expression, reverses high glucose-altered Bcl-2 and cleaved caspase-3 protein expression, and inhibits TGF-β1/Smad signaling. Rhein 8-O-β-D-Glucopyranoside accelerates Sennoside A (HY-N0365) metabolism, stimulates sennoside A purgative activity. Rhein 8-O-β-D-Glucopyranoside inhibits bacterial biofilm formation, suppresses its virulence gene expression, and exerts antibacterial activity. Rhein 8-O-β-D-Glucopyranoside can be used for the research of diabetic nephropathy, constipation, and infection .
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Multiflorin A
Multiflorin A
0 Images
Cat. No.: HY-N12326
CAS No.: 1350028-90-8
Category:  

Flavonoids Prunus humilis (Bge.) Sok. Flavones Rosaceae Extract Plants

Target:  

Cytochrome P450 Quinone Reductase COX

Multiflorin A is an orally active active ingredient of traditional herbal laxative, Pruni semen. Multiflorin A inhibits aromatase enzyme activity with an IC50 of 15.5 μM. Multiflorin A also inhibits quinone reductase 2 (QR2) and COX-2 enzyme. Multiflorin A has purgative activity and reduces postprandial blood glucose in mice. Multiflorin A modulates intestinal glucose transporters, tight junction proteins, and aquaporins, reshapes gut microbiota, and alters faecal metabolites. Multiflorin A can be used for the research of constipation and diabetes .
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Sennoside C (Standard)
Sennoside C (Standard)
0 Images
Cat. No.: HY-N1972R
CAS No.: 37271-16-2
Category:  

Quinones Anthraquinones Phenols Polyphenols Leguminosae Extract Plants Cassia angustifolia

Target:  

Reference Standards Others

Sennoside C (Standard) is the analytical standard of Sennoside C (HY-N1972). This product is intended for research and analytical applications. Sennoside C is an orally active component of the traditional Chinese medicine Sennae Folium. Sennoside C can bind to human lysozyme and inhibit its amyloid fibrosis (IC50: 186.20 μM). Sennoside C has certain purgative activity. Sennoside C can be used in the research of diarrhea and anti-amyloid related diseases .
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Rhein 8-O-β-D-Glucopyranoside (Standard)
Rhein 8-O-β-D-Glucopyranoside (Standard)
0 Images
Cat. No.: HY-N6082R
CAS No.: 34298-86-7
Category:  

Quinones Monophenols Rheum palmatum L. Anthraquinones Phenols Plants Polygonaceae Extract

Target:  

Reference Standards Apoptosis Bacterial Bcl-2 Family Caspase TGF-beta/Smad

Rhein 8-O-β-D-Glucopyranoside (Standard) is the analytical standard of Rhein 8-O-β-D-Glucopyranoside (HY-N6083). This product is intended for research and analytical applications. Rhein 8-O-β-D-Glucopyranoside is an orally active glycoside found in Rhubarb. Rhein 8-O-β-D-Glucopyranoside attenuates high glucose-induced apoptosis, recovers altered lincRNA ANRIL and let-7a expression, reverses high glucose-altered Bcl-2 and cleaved caspase-3 protein expression, and inhibits TGF-β1/Smad signaling. Rhein 8-O-β-D-Glucopyranoside accelerates Sennoside A (HY-N0365) metabolism, stimulates sennoside A purgative activity. Rhein 8-O-β-D-Glucopyranoside inhibits bacterial biofilm formation, suppresses its virulence gene expression, and exerts antibacterial activity. Rhein 8-O-β-D-Glucopyranoside can be used for the research of diabetic nephropathy, constipation, and infection .
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