23 Results for "

pyroglutamic acid

" in MedChemExpress (MCE) Product Catalog:
Products (23)

23 Results for "pyroglutamic acid" in MCE Product Catalog:

5
5 Cited Publications
Cat. No.: HY-15461A
CAS No.: 1210344-83-4
Purity:  99.84%
Synonyms: PF-04971729 L-pyroglutamic acid
Target:  

SGLT

Research Areas:  

Metabolic Disease

Ertugliflozin L-pyroglutamic acid (PF-04971729 L-pyroglutamic acid) is a potent, selective and orally active inhibitor of the sodium-dependent glucose cotransporter 2 (SGLT2), with an IC50 of 0.877 nM for h-SGLT2 . Has the potential for the treatment of type 2 diabetes mellitus .
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3
3 Cited Publications
Cat. No.: HY-76082
CAS No.: 98-79-3
L-Pyroglutamic acid is the levo-isomer of Pyroglutamic acid. L-Pyroglutamic acid is the biologically active enantiomer in humans. Pyroglutamic acid is an intermediate in glutathione metabolism. L-Pyroglutamic acid can be used as a biomarker for systemic lupus erythematosus (SLE) .
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3
3 Cited Publications
Cat. No.: HY-76082A
CAS No.: 28874-51-3
L-Pyroglutamic acid sodium is the levo-isomer of Pyroglutamic acid. L-Pyroglutamic acid sodium is the biologically active enantiomer in humans. Pyroglutamic acid is an intermediate in glutathione metabolism. L-Pyroglutamic acid sodium can be used as a biomarker for systemic lupus erythematosus (SLE) .
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1
1 Cited Publications
Cat. No.: HY-76082S
CAS No.: 1086136-22-2
L-Pyroglutamic acid-d5 is the deuterium labeled L-Pyroglutamic acid (HY-76082). L-Pyroglutamic acid is the levo-isomer of Pyroglutamic acid. L-Pyroglutamic acid is the biologically active enantiomer in humans. Pyroglutamic acid is an intermediate in glutathione metabolism.
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1
1 Cited Publications
Cat. No.: HY-W012738
CAS No.: 149-87-1
Research Areas:  

Infection

DL-Pyroglutamic acid (CAE) as an inactivator of hepatitis B surface, inactivates vaccinia virus, herpes simplex virus, and influenza virus except poliovirus. DL-Pyroglutamic acid is also a possible inhibitor of GABA transaminase, increases GABA amount with antiepileptic action .
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1
1 Cited Publications
Cat. No.: HY-W012738S
CAS No.: 352431-30-2
DL-Pyroglutamic acid-d5 is the deuterium labeled DL-Pyroglutamic acid .
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Cat. No.: HY-Y0973
CAS No.: 56602-33-6
BOP hexafluorophosphate is a phosphonium-type condensing agent. BOP hexafluorophosphate activates the carboxylic acid component to form a highly reactive O-benzotriazole ester (active ester) intermediate, which then reacts with the amino component to form an amide bond (peptide bond). BOP hexafluorophosphate is applicable to solid-phase polypeptide synthesis and nucleoside modification .
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Cat. No.: HY-76082R
CAS No.: 98-79-3
L-Pyroglutamic acid (Standard) is the analytical standard of L-Pyroglutamic acid (HY-76082). This product is intended for research and analytical applications. L-Pyroglutamic acid is the levo-isomer of Pyroglutamic acid. L-Pyroglutamic acid is the biologically active enantiomer in humans. Pyroglutamic acid is an intermediate in glutathione metabolism. L-Pyroglutamic acid standard can be used as a biomarker for systemic lupus erythematosus (SLE) .
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Cat. No.: HY-W011750
CAS No.: 32159-21-0
Synonyms: Cbz-L-pyroglutamic acid
Research Areas:  

Others

Z-Pyr-OH (Cbz-L-pyroglutamic acid) can be used as a biochemical assay reagent .
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Cat. No.: HY-32291
CAS No.: 4931-66-2
Synonyms: (S)-Methyl 5-oxopyrrolidine-2-carboxylate; L-pyroglutamic acid methyl ester
Target:  

NO Synthase

Research Areas:  

Infection Inflammation/Immunology

Methyl L-pyroglutamate ((S)-Methyl 5-oxopyrrolidine-2-carboxylate) is a phenolic compound. Methyl L-pyroglutamate can be isolated from Portulaca oleracea L. Methyl L-pyroglutamate slightly inhibits NO production. Methyl L-pyroglutamate can be used in the research of inflammatory diseases .
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Cat. No.: HY-40269
CAS No.: 7149-65-7
L-Pyroglutamic acid ethyl ester (Compound 2c) is an intermediate. L-Pyroglutamic acid ethyl ester is involved in the synthesis of γ-aminobutyrate transaminase inactivators. L-Pyroglutamic acid ethyl ester can be used in epilepsy and Huntington's disease research .
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Cat. No.: HY-P4886A
Target:  

Amyloid-β

Research Areas:  

Neurological Disease

Amyloid β-Protein (3-42) TFA is a precursor of Pyr peptide. Pyroglutamic acid-modified Aβ (pEAβ) (3-42) is the core of the amyloid plaque in Alzheimer's disease. pEAβ (3-42) accelerates the aggregation of Aβ(1-42), while Aβ(1-42) significantly slows down the primary and secondary nucleation of pEAβ(3-42).
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Cat. No.: HY-76082S1
CAS No.: 55443-56-6
L-Pyroglutamic acid- 13C5 is the 13C labeled L-Pyroglutamic acid (HY-76082) . L-Pyroglutamic acid is the levo-isomer of Pyroglutamic acid. L-Pyroglutamic acid is the levo-isomer of Pyroglutamic acid. L-Pyroglutamic acid is the biologically active enantiomer in humans. Pyroglutamic acid is an intermediate in glutathione metabolism. L-Pyroglutamic acid can be used as a biomarker for systemic lupus erythematosus (SLE) .
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Cat. No.: HY-W009472
CAS No.: 22155-91-5
Synonyms: PYR
Research Areas:  

Others

L-Pyroglutamic acid β-naphthylamide (PYR) is aglutamic acid derivatives.
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Cat. No.: HY-W009673
CAS No.: 53100-44-0
Synonyms: N-Boc-L-pyroglutamic acid
Boc-Pyr-OH is a Boc-protected pyroglutamic acid derivative. Boc-Pyr-OH stabilizes the amino group of pyroglutamic acid through the Boc protecting group, preventing unwanted reactions during peptide synthesis. Boc-Pyr-OH can be used in the research of thyrotropin-releasing hormone (TRH) synthesis .
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Cat. No.: HY-W003605
CAS No.: 144978-35-8
Synonyms: N-Boc-D-pyroglutamic acid ethyl ester
Research Areas:  

Others

Boc-D-Pyr-Oet (N-Boc-D-pyroglutamic acid ethyl ester) is used as a biochemical assay reagent .
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Cat. No.: HY-W003605A
CAS No.: 251924-83-1
Research Areas:  

Others

1-Boc-DL-Pyroglutamic acid ethyl ester is a Boc-protected Pyroglutamic acid derivative, can be used for the synthesis of agents or other compounds .
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Cat. No.: HY-41631
CAS No.: 144978-12-1
Synonyms: (S)-Ethyl-N-Boc-pyroglutamate
Research Areas:  

Others

Boc-Pyr-Oet ((S)-Ethyl-N-Boc-pyroglutamate) is a derivative of L-Pyroglutamic acid (HY-76082). Boc-Pyr-Oet can be used for the synthesis of agents or other compounds.
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Cat. No.: HY-P3174
CAS No.: 9075-21-2
Target:  

Aminopeptidase

Research Areas:  

Inflammation/Immunology

Pyroglutamate aminopeptidase I is a type of enzyme that cleaves the peptide bond of pyroglutamic acid linked to the N-terminal end of a protein, including some important anti-inflammatory proteins like immunoglobulin .
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Cat. No.: HY-W286423
CAS No.: 66642-36-2
L-Pyroglutamic acid 7-amido-4-methylcoumarin is a fluorogenic substrate for pyroglutamate aminopeptidase 1 (PGP-1) .
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