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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
30 Results for "
ros reaction
" in MedChemExpress (MCE) Product Catalog:
Products (30)
30 Results for "ros reaction" in MCE Product Catalog:
22
Category:
Human Gut Microbiota Metabolites Microorganisms Ketones, Aldehydes, Acids Endogenous metabolite
Target:
13
13 Cited Publications
Synonyms: HPF; 3'-p-(Hydroxyphenyl) fluorescein
5
5 Cited Publications
Cat. No.: HY-D1157
CAS No.: 2245230-79-7
4
Target:
Research Areas:
2,7-Dichlorodihydrofluorescein (DCFH2) is a non-fluorescent reactive oxygen species (ROS) probe with an excitation wavelength of 485-500 nm and an emission wavelength of 515-530 nm. 2,7-Dichlorodihydrofluorescein is first hydrolyzed by intracellular esterases and then oxidized by ROS to generate non-biomembrane-permeable, highly fluorescent 2,7-dichlorofluorescein (DCF). The fluorescence intensity of DCF is positively correlated with the ROS concentration. 2,7-Dichlorodihydrofluorescein can undergo oxidation reactions with a variety of ROS (such as ·OH, H2O2, ONOO -, etc.) and is used to quantitatively detect the level of oxidative stress inside and outside cells. It is suitable for oxidative stress analysis in in vitro cell models and in vivo targeted delivery (such as liver-targeted liposomes) .
4
3
3 Cited Publications
Target:
Research Areas:
N-Acetyl-D-cysteine has antioxidant activities and scavenges ROS through the reaction with its thiol group, but cannot enter the glutathione metabolic pathway .
2
2 Cited Publications
Cat. No.: HY-N0735
CAS No.: 104112-82-5
1
1 Cited Publications
Cat. No.: HY-119977
CAS No.: 359010-70-1
Research Areas:
APF is a cell-permeable fluorogenic probe to measure hydroxyly radical of ROS. APF is nonfluorescent and produces bright green fluorescence upon reaction with hydroxyl radical. APF can be used to detect intracellular reactive oxygen species (ROS) (Ex/Em=490/525 nm) .
1
Research Areas:
Sodium metavanadate, 99% (Sodium vanadate (V), 99%) is an orally active phosphate structural analog and protein tyrosine phosphatase (PTPases) inhibitor. Sodium metavanadate, 99% mimics phosphate to interfere with phosphoprotein reactions, inhibits GAPDH, Na +/K +-ATPase and microbial membrane ATPase, and acts as a terminal electron acceptor for anaerobic respiration. Sodium metavanadate, 99% induces ROS production, G2/M phase arrest, mitochondrial membrane potential loss and apoptosis in breast cancer cells, and reduces tumor volume in tumor-bearing mice. Sodium metavanadate, 99% also exhibits oral insulin-sensitizing and metabolic regulatory activities, and reduces plasmodium parasitemia levels. Sodium metavanadate, 99% can be used in studies related to cadmium exposure-induced metabolic syndrome, plasmodium infection, breast cancer and type 1 diabetes .
Synonyms: L-Cysteinylglycine; Cys-Gly; H-Cys-Gly-OH
Cat. No.: HY-W004761
CAS No.: 13675-18-8
Synonyms: Hypodiboric acid
Cat. No.: HY-Y0319G
CAS No.: 16674-78-5
Research Areas:
Ferumoxytol is an FDA-approved ultrasmall superparamagnetic iron oxide preparation and iron replacement agent that exerts selective activity against leukemia cells with low ferroportin expression. Ferumoxytol increases intracellular iron levels, induces reactive oxygen species (ROS) production via the Fenton reaction, and triggers oxidative stress and cell death. Ferumoxytol reduces disease burden in mouse models and patient-derived leukemia models. As an MRI contrast agent, Ferumoxytol enables imaging of vascular lesions, tumors and lymph nodes. Ferumoxytol can be used in research related to acute myeloid leukemia and blast-phase chronic myeloid leukemia .
Cat. No.: HY-W006398S
CAS No.: 39230-37-0
Synonyms: Anhydrous sodium acetate-d3
Cat. No.: HY-DY1035
CAS No.: 359010-69-8
Solvent and concentration: DMSO: 10 mM
Target:
Research Areas:
Acetic acid sodium (Standard) (Anhydrous sodium acetate (Standard) is the analytical standard of Anhydrous sodium acetate. This product is intended for research and analytical applications. Acetic acid is a carboxylic acid and short-chain fatty acid (SCFAs). Acetic acid activates AMPK, increases ROS, cleaved caspase 9, PPARα, downregulates SREBP-1c, ChREBP expression. Acetic acid exhibits antifungal activity against Saccharomyces cerevisiae W303-1A. Acetic acid regulates energy metabolism. Acetic acid has anticancer activity against gastric cancer. Acetic acid induces writhing reaction and ulcerative colitis. Acetic acid can be used in the researches for gastric cancer, ulcerative colitis, hepatic steatosis, and pain .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
