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tocolytic agent

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Drug Derivative (2) Oxytocin Receptor (9) Reference Standards (3) Vasopressin Receptor (4)
By Research Areas:	Cancer (4) Cardiovascular Disease (2) Endocrinology (9) Metabolic Disease (2) Neurological Disease (2)

Inhibitors & Agonists

Biochemical Assay Reagents

Peptides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-17572

Atosiban 5+ Cited Publications RW22164; RWJ22164	Oxytocin Receptor Vasopressin Receptor	Cardiovascular Disease Endocrinology Cancer
Atosiban (RW22164; RWJ22164) is a nonapeptide competitive vasopressin/oxytocin receptor antagonist, and is a desamino-oxytocin analogue. Atosiban is the main tocolytic agent and has the potential for spontaneous preterm labor research .

HY-108677

L-368,899 hydrochloride Maximum Cited Publications 7 Publications Verification	Oxytocin Receptor	Endocrinology
L-368,899 hydrochloride is a potent, selective, orally bioavailable, non-peptide oxytocin receptor antagonist, with IC₅₀s of 8.9 nM and 26 nM for rat uterus and human uterus oxytocin receptor, respectively. L-368,899 hydrochloride used as a tocolytic agent .

HY-17572A

Atosiban acetate 5+ Cited Publications RW22164 acetate; RWJ22164 acetate	Oxytocin Receptor Vasopressin Receptor	Cardiovascular Disease Endocrinology Cancer
Atosiban acetate (RW22164 acetate;RWJ22164 acetate) is a nonapeptide competitive vasopressin/oxytocin receptor antagonist, and is a desamino-oxytocin analogue. Atosiban is the main tocolytic agent and has the potential for spontaneous preterm labor research .

HY-W587861

5β-Dihydroprogesterone 1 Publications Verification 5βDHP	Oxytocin Receptor	Endocrinology
5β-Dihydroprogesterone (5βDHP) is the metabolite of Progesterone (HY-N0437). 5β-Dihydroprogesterone binds to oxytocin receptor, reduces the Oxytocin (HY-17571)-induced calcium signal transduction, thereby exhibiting the tocolytic activity .

HY-W094475D

Magnesium sulfate heptahydrate, meets analytical specification of Ph. Eur. BP USP FCC Epsom salts, meets analytical specification of Ph. Eur. BP USP FCC	Drug Derivative	Neurological Disease Metabolic Disease
Magnesium sulfate heptahydrate, meets analytical specification of Ph. Eur. BP USP FCC (Epsom salts, meets analytical specification of Ph. Eur. BP USP FCC) is currently the anticonvulsant of choice for the prevention and control of eclamptic fits and is also widely used as a tocolytic agent .

HY-W094475E

Magnesium sulfate heptahydrate, United States Pharmacopeia (USP) Reference Standard Epsom salts (Pharmaceutical primary standard, USP)	Drug Derivative	Neurological Disease Metabolic Disease
Magnesium sulfate heptahydrate, United States Pharmacopeia (USP) Reference Standard (Epsom salts (Pharmaceutical primary standard, USP)) is currently the anticonvulsant of choice for the prevention and control of eclamptic fits and is also widely used as a tocolytic agent .

HY-17572R

Atosiban (Standard) RW22164 (Standard); RWJ22164 (Standard)	Reference Standards Oxytocin Receptor Vasopressin Receptor	Endocrinology Cancer
Atosiban (Standard) is the analytical standard of Atosiban. This product is intended for research and analytical applications. Atosiban (RW22164; RWJ22164) is a nonapeptide competitive vasopressin/oxytocin receptor antagonist, and is a desamino-oxytocin analogue. Atosiban is the main tocolytic agent and has the potential for spontaneous preterm labor research .

HY-17572AR

Atosiban acetate (Standard) RW22164 acetate (Standard); RWJ22164 acetate (Standard)	Reference Standards Oxytocin Receptor Vasopressin Receptor	Endocrinology Cancer
Atosiban (acetate) (Standard) is the analytical standard of Atosiban (acetate). This product is intended for research and analytical applications. Atosiban acetate (RW22164 acetate;RWJ22164 acetate) is a nonapeptide competitive vasopressin/oxytocin receptor antagonist, and is a desamino-oxytocin analogue. Atosiban is the main tocolytic agent and has the potential for spontaneous preterm labor research .

HY-15018A

SSR126768A free base	Oxytocin Receptor	Endocrinology
SSR126768A free base is an orally active antagonist for oxytocin receptor, with K_i of 0.44 nM. SSR126768A free base is a tocolytic agent, that antagonizes the Oxytocin (HY-17571)-induced intracellular Ca ²⁺ increase and prostaglandin release in human uterine smooth muscle cells, inhibits thus the Oxytocin (HY-17571)-induced uterine contraction and delays parturition in pregnant rats in labor .

HY-15007

L 366509	Oxytocin Receptor	Endocrinology
L 366509 is a spiroindenylpiperidine camphorsulfonamide oxytocin (OT) antagonist. Modifications led to a new series of o-tolylpiperazine (TP) camphorsulfonamides, exhibiting high affinity for OT receptors and selectivity over arginine vasopressin receptors. Notably, compound 7 (L-368,899) showed excellent OT receptor affinity, potency in inhibiting OT-stimulated uterine contractions, good aqueous solubility, and oral bioavailability in multiple species. Compound 7 has entered clinical testing as an oral and intravenous tocolytic agent. Molecular modeling suggests the TP camphorsulfonamide structure mimics the D-AA2-Ile3 dipeptide, crucial in potent OT antagonists .

HY-108677R

L-368,899 hydrochloride (Standard)	Reference Standards Oxytocin Receptor	Endocrinology
L-368,899 hydrochloride (Standard) is the analytical standard of L-368,899 hydrochloride (HY-108677). This product is intended for research and analytical applications. L-368,899 hydrochloride is a potent, selective, orally bioavailable, non-peptide oxytocin receptor antagonist, with IC₅₀s of 8.9 nM and 26 nM for rat uterus and human uterus oxytocin receptor, respectively. L-368,899 hydrochloride used as a tocolytic agent .

Magnesium sulfate heptahydrate, meets analytical specification of Ph. Eur. BP USP FCC Epsom salts, meets analytical specification of Ph. Eur. BP USP FCC	Biochemical Assay Reagents
Magnesium sulfate heptahydrate, meets analytical specification of Ph. Eur. BP USP FCC (Epsom salts, meets analytical specification of Ph. Eur. BP USP FCC) is currently the anticonvulsant of choice for the prevention and control of eclamptic fits and is also widely used as a tocolytic agent .

Magnesium sulfate heptahydrate, United States Pharmacopeia (USP) Reference Standard Epsom salts (Pharmaceutical primary standard, USP)	Biochemical Assay Reagents
Magnesium sulfate heptahydrate, United States Pharmacopeia (USP) Reference Standard (Epsom salts (Pharmaceutical primary standard, USP)) is currently the anticonvulsant of choice for the prevention and control of eclamptic fits and is also widely used as a tocolytic agent .

Cat. No.	Product Name	Target	Research Area

HY-17572

Atosiban 5+ Cited Publications RW22164; RWJ22164	Oxytocin Receptor Vasopressin Receptor	Cardiovascular Disease Endocrinology Cancer
Atosiban (RW22164; RWJ22164) is a nonapeptide competitive vasopressin/oxytocin receptor antagonist, and is a desamino-oxytocin analogue. Atosiban is the main tocolytic agent and has the potential for spontaneous preterm labor research .

HY-17572A

Atosiban acetate 5+ Cited Publications RW22164 acetate; RWJ22164 acetate	Oxytocin Receptor Vasopressin Receptor	Cardiovascular Disease Endocrinology Cancer
Atosiban acetate (RW22164 acetate;RWJ22164 acetate) is a nonapeptide competitive vasopressin/oxytocin receptor antagonist, and is a desamino-oxytocin analogue. Atosiban is the main tocolytic agent and has the potential for spontaneous preterm labor research .

HY-17572R

Atosiban (Standard) RW22164 (Standard); RWJ22164 (Standard)	Reference Standards Oxytocin Receptor Vasopressin Receptor	Endocrinology Cancer
Atosiban (Standard) is the analytical standard of Atosiban. This product is intended for research and analytical applications. Atosiban (RW22164; RWJ22164) is a nonapeptide competitive vasopressin/oxytocin receptor antagonist, and is a desamino-oxytocin analogue. Atosiban is the main tocolytic agent and has the potential for spontaneous preterm labor research .

HY-17572AR

Atosiban acetate (Standard) RW22164 acetate (Standard); RWJ22164 acetate (Standard)	Reference Standards Oxytocin Receptor Vasopressin Receptor	Endocrinology Cancer
Atosiban (acetate) (Standard) is the analytical standard of Atosiban (acetate). This product is intended for research and analytical applications. Atosiban acetate (RW22164 acetate;RWJ22164 acetate) is a nonapeptide competitive vasopressin/oxytocin receptor antagonist, and is a desamino-oxytocin analogue. Atosiban is the main tocolytic agent and has the potential for spontaneous preterm labor research .

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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