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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
6 Results for "
trans-Golgi network
" in MedChemExpress (MCE) Product Catalog:
Products (6)
6 Results for "trans-Golgi network" in MCE Product Catalog:
2
2 Cited Publications
Retro-2 is a selective inhibitor of retrograde protein trafficking at the endosome-trans-Golgi network interface. Retro-2 is an ebolavirus (EBOV) infection inhibitor with an EC50 of 12.2 μM in HeLa cells. Retro-2 induces cell autophagy .
Target:
Research Areas:
Exo2 is a secretion inhibitor. Exo2 perturbs trafficking of Shiga toxin between endosomes and the trans-Golgi network. Exo2 blocks secretory cargo exit from the ER (endoplasmic reticulum) and disrupts the Golgi apparatus, but does not affect the morphology of the TGN (trans-Golgi network) Exo2 can stimulate calcium-dependent exocytosis in permeabilized adrenal chromaff in cells .
Target:
Research Areas:
NPPM 6748-481 is a potent and selective yeast Sec14 inhibitor with a yeast Sec14 IC50 of 211 nM. NPPM 6748-481 disrupts membrane trafficking, impairing trans-Golgi network-endosomal transport and endocytic transport. NPPM 6748-481 impairs Snc1 v-SNARE recycling, secretory invertase trafficking, and vacuolar carboxypeptidase Y processing. NPPM 6748-481 can be used for research on yeast infection .
Cat. No.: HY-122740
CAS No.: 313683-81-7
Retro-1 is a toxin inhibitor. Retro-1 blocks the retrograde transport of STxB to the trans-Golgi network/Golgi. Retro-1 inhibits the cytotoxic effects of Ricin, bacterial toxins Stx1 and Stx2. Retro-1 can also substantially enhance the effectiveness of antisense and splice switching oligonucleotides .
Cat. No.: HY-P71030
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TGOLN2; trans-Golgi network Glycoprotein 48; trans-Golgi network Protein 2; trans-Golgi network Glycoprotein 51; TGN51; TGN38 Homolog; TGN46; HTGN46; TGN48; HTGN48; TGN38; HTGN51; TTGN2; trans-Golgi network Protein (46, 48, 51kD Isoforms); trans-Golgi Net
Species:
Human
Source:
HEK293
Cat. No.: HY-E70190
Synonyms: EC:2.8.2.20; TPST2
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
