8 Results for "

zymogen activation

" in MedChemExpress (MCE) Product Catalog:
Products (8)

8 Results for "zymogen activation" in MCE Product Catalog:

Cat. No.: HY-P99415
CAS No.: 2098724-83-3
Synonyms: MAA868

Target:  

Factor Xa

Research Areas:  

Cardiovascular Disease

Abelacimab (MAA868) is a fully human IgG1 monoclonal antibody that binds with high affinity to the catalytic structural domain of FXI and locks it in the zymogen conformation, thereby preventing its activation by FXIIa or thrombin. Abelacimab can be used in thromboembolic disease studies .
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Cat. No.: HY-144813
CAS No.: 1627094-88-5
Purity:  98.13%
Target:  

Cathepsin

Research Areas:  

Inflammation/Immunology Cancer

Gü2602 is a potent, reversible cathepsin K (CatK) inhibitor with a Ki of 0.013 nM for mature CatK (mCatK). Gü2602 suppresses the autocatalytic activation of the cathepsin K zymogen .
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Cat. No.: HY-E70391
Target:  

Others

Research Areas:  

Others

C1r Enzyme is the activated form of the C1r zymogen and serves as an activator of Cls .
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Cat. No.: HY-144812
CAS No.: 1043922-53-7
Target:  

Cathepsin

Research Areas:  

Inflammation/Immunology Cancer

Gü1303 is a potent, reversible, slow-binding cathepsin K (CatK) inhibitor with a Ki of 0.91 nM for mature CatK (mCatK). Gü1303 suppresses the autocatalytic activation of the cathepsin K zymogen .
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Cat. No.: HY-E70533
Target:  

Complement System

Research Areas:  

Inflammation/Immunology

C1r proenzyme, the native form of C1r enzyme, is an inactive zymogen until C1 is activated. C1r is activated when C1 binds to and is activated by antibodies bound to antigens (immune complexes) yielding C1r enzyme .
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Cat. No.: HY-E70534
Target:  

Complement System

Research Areas:  

Inflammation/Immunology

C1s Proenzyme, the native form of C1s enzyme, is an inactive zymogen until C1 is activated. C1 complex binds to and is activated by antigen-antibody complexes (immune complexes) yielding C1r enzyme. C1r enzyme in the C1 complex activates C1s proenzyme generating C1s enzyme .
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Cat. No.: HY-P3118
CAS No.: 1325307-57-0
Research Areas:  

Others

Bz-IEGR-pNA acetate is a trypsin substrate that can be hydrolyzed by prostate kinase release enzyme-related peptide KLKs .
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Cat. No.: HY-P2974A
Target:  

Elastase

Research Areas:  

Metabolic Disease

Elastase, Rat (EC 3.4.21.35) is a form of elastase that is produced in the acinar cells of the pancreas, initially produced as an inactive zymogen and later activated in the duodenum by trypsin. Elastases form a subfamily of serine proteases, characterized by a distinctive structure consisting of two beta-barrel domains converging at the active site that hydrolyze amides and esters amongst many proteins in addition to elastin, a type of connective tissue that holds organs together.
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