PLGF
Placental growth factor (PlGF) is the VEGF family member that binds VEGFR1 and neuropilin-1 but not VEGFR2, and is expressed chiefly by placental trophoblast, with lower levels in lung, thyroid, and other tissues. Rather than driving baseline angiogenesis, PlGF amplifies pathological neovascularization and inflammation: it displaces VEGF-A from VEGFR1, recruits monocytes and mast cells, and synergizes with VEGF-A in tumor, ischemic, and diabetic disease. Reduced circulating PlGF with elevated sFlt-1 is a diagnostic signal of preeclampsia. Recombinant PlGF supports VEGFR1-specific binding and functional assays, antibody neutralization studies, and research on placental and angiogenic disorders.
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PLGF Recombinant Proteins (10)
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Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
- Formula: Human
- Molecular Weight: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
