3-Methyl-2-oxobutanoic acid-¹³C₄,d₄ sodium

Name: 3-Methyl-2-oxobutanoic acid- 13 C 4 ,d 4 sodium
Brand: MedChemExpress
SKU: HY-W006057AS2
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Cat. No.: HY-W006057AS2 Purity: 98.0%: Data Sheet
COA

SDS
Handling Instructions
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Sodium 3-methyl-2-oxobutanoate-¹³C₄,d₄ is the deuterium and ¹³C labeled Sodium 3-methyl-2-oxobutanoate.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

3-Methyl-2-oxobutanoic acid-<sup>13</sup>C<sub>4</sub>,d<sub>4</sub> sodium

3-Methyl-2-oxobutanoic acid-¹³C₄,d₄ sodium 화학구조

CAS No. : 1185115-88-1

사이즈	재고	수량
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in Water ready for reconstitution	견적 받기 2-4 weeks 2-4 weeks 2-4 weeks 2-4 weeks	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in Water	견적 받기 2-4 weeks 2-4 weeks 2-4 weeks 2-4 weeks	Estimated Time of Arrival: December 31
Solid
5 mg	해외재고보유	Estimated Time of Arrival: December 31
10 mg	해외재고보유	Estimated Time of Arrival: December 31
25 mg	해외재고보유	Estimated Time of Arrival: December 31
50 mg	견적 받기
100 mg	견적 받기

or 대량구매 문의

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

This product is a controlled substance and not for sale in your territory.

고객리뷰

Based on 1 Customer Validation

Other Forms of 3-Methyl-2-oxobutanoic acid-¹³C₄,d₄ sodium:

Sodium 3-methyl-2-oxobutanoate In-stock

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Biological Activity
순도&문서
References
고객리뷰

제품 설명

Sodium 3-methyl-2-oxobutanoate-¹³C₄,d₄ is the deuterium and ¹³C labeled Sodium 3-methyl-2-oxobutanoate^[1].

Application

1. This compound can be used as a tracer.
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

분자량

146.09

화학식

C¹³C₄H₃D₄NaO₃

CAS No.

1185115-88-1

Unlabeled CAS

3715-29-5

Appearance

Solid

Color

White to off-white

SMILES

[2H]C([2H])([13C]([13CH3])([13C]([13C](O[Na])=O)=O)[2H])[2H]

선적

Room temperature in continental US; may vary elsewhere.

보관

-20°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

용액&용해도

In Vitro:

H₂O : 250 mg/mL (1711.27 mM; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	6.8451 mL	34.2255 mL	68.4510 mL
5 mM	1.3690 mL	6.8451 mL	13.6902 mL
10 mM	0.6845 mL	3.4225 mL	6.8451 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

몰농도 계산기
농도 희석 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

순도&문서

Purity: 98.0%

Select Batch:

Data Sheet (274 KB) SDS (252 KB)

COA (253 KB)

Handling Instructions (2659 KB)

References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	6.8451 mL	34.2255 mL	68.4510 mL	171.1274 mL
	5 mM	1.3690 mL	6.8451 mL	13.6902 mL	34.2255 mL
	10 mM	0.6845 mL	3.4225 mL	6.8451 mL	17.1127 mL
	15 mM	0.4563 mL	2.2817 mL	4.5634 mL	11.4085 mL
	20 mM	0.3423 mL	1.7113 mL	3.4225 mL	8.5564 mL
	25 mM	0.2738 mL	1.3690 mL	2.7380 mL	6.8451 mL
	30 mM	0.2282 mL	1.1408 mL	2.2817 mL	5.7042 mL
	40 mM	0.1711 mL	0.8556 mL	1.7113 mL	4.2782 mL
	50 mM	0.1369 mL	0.6845 mL	1.3690 mL	3.4225 mL
	60 mM	0.1141 mL	0.5704 mL	1.1408 mL	2.8521 mL
	80 mM	0.0856 mL	0.4278 mL	0.8556 mL	2.1391 mL
	100 mM	0.0685 mL	0.3423 mL	0.6845 mL	1.7113 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.