1. Anti-infection Metabolic Enzyme/Protease
  2. Fungal Cytochrome P450
  3. Solavetivone

Solavetivone is a Sesquiterpenoid phytoalexin and Antifungal agent. Solavetivone is isolated from stress-challenged potato plants. Solavetivone is hydroxylated by sesquiterpenoid phytoalexin hydroxylase (SPH/CYP76A2L). Solavetivone helps solanaceous plants defend against pathogens, damages plant cells after pathogen threat, and inhibits mycelial growth of Rhizoctonia solani. Solavetivone is applicable to studies related to Rhizoctonia solani infection.

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Solavetivone

Solavetivone 화학구조

CAS No. : 54878-25-0

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제품 설명

Solavetivone is a Sesquiterpenoid phytoalexin and Antifungal agent. Solavetivone is isolated from stress-challenged potato plants. Solavetivone is hydroxylated by sesquiterpenoid phytoalexin hydroxylase (SPH/CYP76A2L). Solavetivone helps solanaceous plants defend against pathogens, damages plant cells after pathogen threat, and inhibits mycelial growth of Rhizoctonia solani. Solavetivone is applicable to studies related to Rhizoctonia solani infection[1][2][3].

IC50 & Target[1]

CYP76A2L

 

Cellular Effect
Cell Line Type Value Description References
OVCAR-3 IC50
0.1 mM
Compound: 1, Solavetivone
Cytotoxicity against human OVCAR-3 cells
Cytotoxicity against human OVCAR-3 cells
[PMID: 11575964]
In Vitro

Solavetivone (3.2-16.1 μg/mL; 48 h) inhibits in vitro mycelial growth of Rhizoctonia solani in a concentration-dependent manner, with 27.6% inhibition observed at 16.1 μg/mL after 48 h incubation[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

분자량

218.33

화학식

C15H22O

CAS No.
SMILES

C[C@H]1[C@@]2(C(C)=CC(C1)=O)C[C@@H](CC2)C(C)=C

Structure Classification
Initial Source
선적

Room temperature in continental US; may vary elsewhere.

보관

Please store the product under the recommended conditions in the Certificate of Analysis.

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상품명:
Solavetivone
Cat. No.:
HY-N12475
수량:
MCE Japan Authorized Agent: