Cytotoxic and novel compounds from Solanum indicum
- J Nat Prod. 2001 Sep;64(9):1232-3. doi: 10.1021/np010186v.
Affiliations
- 1. Institute of Microbiology and Immunology, National Yang-Ming University, Taipei 112, Taiwan.
PMID: 11575964
DOI: 10.1021/np010186v
Abstract
Solavetivone (1), cytotoxic to OVCAR-3 cells with an IC(50) value of 0.1 mM, has been isolated from Solanum indicum. In addition, a novel solafuranone (2) and three known compounds, scopoletin, N-(p-trans-coumaroyl)tyramine, and N-trans-feruloyltyramine, were isolated for the first time from this plant. The structures of the above compounds were established by means of spectroscopic and X-ray analyses.