SR 13668
SR13668 is a potent indole analog derived from indole-3-carbinol (I3C), known for its natural anticancer properties but limited by poor metabolic characteristics. Developed to enhance I3C's anticancer efficacy, SR13668 effectively inhibits growth factor-stimulated Akt activation. It demonstrates strong oral anticancer activity across different cancer types in preclinical studies, showing promise in clinical development due to its favorable safety profile and potent therapeutic effects.
For research use only. We do not sell to patients.
- CAS No.: 637774-61-9
- Formula: C25H22N2O5
- Molecular Weight:430.45
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| MCF7 | IC50 |
0.19 μM
Compound: 37, SR-13668
|
Antitumor activity against MCF7 cells
Antitumor activity against MCF7 cells
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[PMID: 17602463] |
Chemical Information
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CAS No. 637774-61-9
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Molecular Weight 430.45
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Formula C25H22N2O5
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SMILES
O=C(C1=CC2=C(NC3=C2C=C4C(NC5=C4C=C(C(OCC)=O)C=C5)=C3OC)C=C1)OCC
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)