T 588
T 588 is an orally active neuroprotective agent. T 588 can increase acetylcholine release from the frontal cortex and hippocampus and meliorate cognitive dysfunction. T 588 can protect cerebellar granule cells from glutamate neurotoxicity. T 588can be used for the research of neurological disease, such as Alzheimer's disease.
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- CAS. Nr.: 142935-03-3
- Formel: C16H24ClNO2S
- Molecular Weight:329.89
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
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Help & FAQs
Biologische Aktivität
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Wobbler mice (model of motoneuron disease (MND))[1]
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Dosage:3, 10 and 30 mg/kg
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Administration:Orally administration, daily for 4 weeks
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Result:Potentiated grip strength, attenuated forelimb contracture and increased the weight of the biceps muscles.
Retarded denervation muscle atrophy and elevated activities of choline acetyltransferase (ChAT) or lactate dehydrogenase in the biceps muscles.
Chemical Information
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CAS. Nr. 142935-03-3
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Molecular Weight 329.89
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Formel C16H24ClNO2S
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SMILES
CCN(CC)CCOC[C@@H](C1=CC=C(SC=C2)C2=C1)O.Cl
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
T 588 Related Classifications
HY-105181 Related Classifications
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