2. Membrane Transporter/Ion Channel
  3. ATP Synthase
  4. Triciribine phosphate sodium

Triciribine phosphate sodium  (Synonyms: TCN-P sodium)

Cat. No.: HY-10250A Purity: 99.82%
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Triciribine phosphate sodium inhibits amidophosphoribosyltransferase by an allosteric mechanism which affects the first committed step of de novo purine biosynthesis. Triciribine phosphate sodium also inhibits IMP dehydrogenase which is the first committed step of guanosine nucleotide synthesis. Tricilibine phosphate does not affect ligase activity.

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Triciribine phosphate sodium Chemical Structure

Triciribine phosphate sodium Chemical Structure

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5 mg USD 435 In-stock
10 mg USD 700 In-stock
25 mg USD 1400 In-stock
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Based on 1 publication(s) in Google Scholar

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Triciribine phosphate sodium Related Antibodies

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Description

Triciribine phosphate sodium inhibits amidophosphoribosyltransferase by an allosteric mechanism which affects the first committed step of de novo purine biosynthesis. Triciribine phosphate sodium also inhibits IMP dehydrogenase which is the first committed step of guanosine nucleotide synthesis. Tricilibine phosphate does not affect ligase activity[1].

Molecular Weight

422.27

Formula

C13H16N6NaO7P
Appearance

Solid

Color

White to light yellow

SMILES

NC1=NN(C)C2=C3C1=CN([C@@H]4O[C@@H]([C@H]([C@H]4O)O)COP(O)(O[Na])=O)C3=NC=N2
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Room temperature in continental US; may vary elsewhere.
Storage

-20°C, stored under nitrogen, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 62.5 mg/mL (148.01 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.3682 mL 11.8408 mL 23.6815 mL
5 mM 0.4736 mL 2.3682 mL 4.7363 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

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Please enter the basic information of animal experiments:

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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.3682 mL 11.8408 mL 23.6815 mL 59.2038 mL
5 mM 0.4736 mL 2.3682 mL 4.7363 mL 11.8408 mL
10 mM 0.2368 mL 1.1841 mL 2.3682 mL 5.9204 mL
15 mM 0.1579 mL 0.7894 mL 1.5788 mL 3.9469 mL
20 mM 0.1184 mL 0.5920 mL 1.1841 mL 2.9602 mL
25 mM 0.0947 mL 0.4736 mL 0.9473 mL 2.3682 mL
30 mM 0.0789 mL 0.3947 mL 0.7894 mL 1.9735 mL
40 mM 0.0592 mL 0.2960 mL 0.5920 mL 1.4801 mL
50 mM 0.0474 mL 0.2368 mL 0.4736 mL 1.1841 mL
60 mM 0.0395 mL 0.1973 mL 0.3947 mL 0.9867 mL
80 mM 0.0296 mL 0.1480 mL 0.2960 mL 0.7400 mL
100 mM 0.0237 mL 0.1184 mL 0.2368 mL 0.5920 mL
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Triciribine phosphate sodium Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Triciribine phosphateTCN-PATP SynthaseAmidophosphoribosyltransferase InhibitorIMP dehydrogenase InhibitorInhibitorinhibitorinhibit

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