Triciribine phosphate sodium
Based on 1 Customer Validation
Triciribine phosphate sodium inhibits amidophosphoribosyltransferase by an allosteric mechanism which affects the first committed step of de novo purine biosynthesis. Triciribine phosphate sodium also inhibits IMP dehydrogenase which is the first committed step of guanosine nucleotide synthesis. Tricilibine phosphate does not affect ligase activity.
For research use only. We do not sell to patients.
- Purity: 99.82%
- Formula: C13H16N6NaO7P
- Molecular Weight:422.27
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Storage:
-20°C, stored under nitrogen, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture)
Biological Activity
Chemical Information
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Appearance Solid
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Molecular Weight 422.27
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Formula C13H16N6NaO7P
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Color White to light yellow
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SMILES
NC1=NN(C)C2=C3C1=CN([C@@H]4O[C@@H]([C@H]([C@H]4O)O)COP(O)(O[Na])=O)C3=NC=N2
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Synonyms
TCN-P sodium
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, stored under nitrogen, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture)
Solvent & Solubility
DMSO : 62.5 mg/mL (148.01 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (271 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.3682 mL | 11.8408 mL | 23.6815 mL | 59.2038 mL |
| 5 mM | 0.4736 mL | 2.3682 mL | 4.7363 mL | 11.8408 mL | |
| 10 mM | 0.2368 mL | 1.1841 mL | 2.3682 mL | 5.9204 mL | |
| 15 mM | 0.1579 mL | 0.7894 mL | 1.5788 mL | 3.9469 mL | |
| 20 mM | 0.1184 mL | 0.5920 mL | 1.1841 mL | 2.9602 mL | |
| 25 mM | 0.0947 mL | 0.4736 mL | 0.9473 mL | 2.3682 mL | |
| 30 mM | 0.0789 mL | 0.3947 mL | 0.7894 mL | 1.9735 mL | |
| 40 mM | 0.0592 mL | 0.2960 mL | 0.5920 mL | 1.4801 mL | |
| 50 mM | 0.0474 mL | 0.2368 mL | 0.4736 mL | 1.1841 mL | |
| 60 mM | 0.0395 mL | 0.1973 mL | 0.3947 mL | 0.9867 mL | |
| 80 mM | 0.0296 mL | 0.1480 mL | 0.2960 mL | 0.7400 mL | |
| 100 mM | 0.0237 mL | 0.1184 mL | 0.2368 mL | 0.5920 mL |