Tubulin/PARP-IN-2
Tubulin/PARP-IN-2 (compound 14) is a dual PARP-Tubulin inhibitor. Tubulin/PARP-IN-2 inhibits PARP1, PARP2, and tubulin activity with IC50 values of 74 nM, 109 nM, and 1.4 µM, respectively. Tubulin/PARP-IN-2 induces apoptosis as well as autophagy. Tubulin/PARP-IN-2 causes cell cycle arrest at the G2/M phase.
For research use only. We do not sell to patients.
- Formula: C19H11FO3
- Molecular Weight:306.29
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| Ishikawa | IC50 |
1 μM
Compound: 25
|
Antiproliferative activity against human Ishikawa cells assessed as reduction in cell growth incuabted for 48 hrs by MTT assay
Antiproliferative activity against human Ishikawa cells assessed as reduction in cell growth incuabted for 48 hrs by MTT assay
|
[PMID: 38823265] |
Chemical Information
-
Molecular Weight 306.29
-
Formula C19H11FO3
-
SMILES
O=C1C=C(OC2=C1C=CC(C3=COC=C3)=C2)C4=CC=C(F)C=C4
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Tubulin/PARP-IN-2 Related Classifications
HY-157320 Related Classifications
Powered by Bioz