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Tuparstobart

(Synonyms: Incagn-02385)
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Based on 1 Customer Validation

Tuparstobart (Incagn-02385) is an IgG1κ antibody targeting LAG-3. LAG-3 is an immune checkpoint receptor protein mainly expressed on activated T cells, NK cells, B cells and plasmacytoid dendritic cells.

For research use only. We do not sell to patients.

  • Purity: 97.65%
  • CAS No.: 2649466-03-3
  • Molecular Weight:145.699 kDa
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Tuparstobart
  • Experimental Validation Results for Tuparstobart
  • Experimental Validation Results for Tuparstobart
  • Tuparstobart Chemical Structure
    Tuparstobart Chemical Structure
CAS No.: 2649466-03-3
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To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
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Assay Types
  • 1/16

    Human IgG1 kappa

  • 1/16

    Immobilized LAG-3 Protein, Human (HEK293, His, HY-P70722) can bind Tuparstobart. The EC50 for this effect is 67.31 ng/mL.

  • 1/16

    Flow cytometric analysis of 1X106 Jurkat cells with Tuparstobart (HY-P990046, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Alexa Fluor 488-conjugated AffiniPure Goat Anti-Human IgG H&L (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).

  • Tuparstobart Chemical Structure
    1/16
  • Tuparstobart
  • Immobilized LAG-3 Protein, Human (HEK293, His, HY-P70722) can bind Tuparstobart. The EC50 for this effect is 67.31 ng/mL.
  • Flow cytometric analysis of 1X106 Jurkat cells with Tuparstobart (HY-P990046, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Alexa Fluor 488-conjugated AffiniPure Goat Anti-Human IgG H&L (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).