L-689560
Based on 1 Customer Validation
L-689560 is a potent N-methyl-D-aspartate (NMDA) receptor antagonist at the GluN1 glycine binding site. L-689560 is widely used as a radiolabeled ligand in binding studies and used for study the roles of NMDA receptors in normal neurological processes as well as in diseases.
For research use only. We do not sell to patients.
- Purity: 99.29%
- CAS No.: 139051-78-8
- Formula: C17H15Cl2N3O3
- Molecular Weight:380.23
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
All iGluR Isoforms
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Biological Activity
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NMDA Receptor |
L-689560 is a 2-carboxytetrahydroquinoline antagonist[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Adult male Sprague-Dawley (SD) rats middle cerebral artery occlusion (MCAO) model[1]
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Dosage:1 mg/kg
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Administration:IP
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Result:Significantly reduced the neuroprotective effect of glycine after glycine receptors.
Chemical Information
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CAS No. 139051-78-8
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Appearance Solid
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Molecular Weight 380.23
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Formula C17H15Cl2N3O3
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Color White to off-white
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SMILES
O=C([C@@H]1NC2=C(C(Cl)=CC(Cl)=C2)[C@@H](NC(NC3=CC=CC=C3)=O)C1)O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Purity & Documentation
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Data Sheet (274 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)