UNC0642 (Standard)
UNC0642 (Standard) is the analytical standard of UNC0642. This product is intended for research and analytical applications. UNC0642 is a potent and selective lysine methyltransferases G9a and GLP inhibitor, with an IC50 of <2.5 nM for G9a.
For research use only. We do not sell to patients.
- Purity: 98%
- CAS No.: 1481677-78-4
- Formula: C29H44F2N6O2
- Molecular Weight:546.70
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Product Information
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 1481677-78-4
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Molecular Weight 546.70
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Formula C29H44F2N6O2
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SMILES
CC(N1CCC(NC2=C3C=C(OC)C(OCCCN4CCCC4)=CC3=NC(N5CCC(F)(F)CC5)=N2)CC1)C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Liu F, et al. Discovery of an in vivo chemical probe of the lysine methyltransferases G9a and GLP. J Med Chem. 2013 Nov 14;56(21):8931-8942. [Content Brief]
[2]. Wang L, et al. Targeting EHMT2 reverses EGFR-TKI resistance in NSCLC by epigenetically regulating the PTEN/AKT signaling pathway. Cell Death Dis. 2018 Jan 26;9(2):129 [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)