Type II TRK inhibitor 3
Type II TRK inhibitor 3 (Compound 18d) is a Type II TRK inhibitor with IC50 values of 0.82, 1.82, and 0.12 nM for TRKAWT/G595R/G667C, respectively. Type II TRK inhibitor 3 exhibits antitumor activity.
For research use only. We do not sell to patients.
- Formula: C29H27N7O
- Molecular Weight:489.57
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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Molecular Weight 489.57
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Formula C29H27N7O
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SMILES
CC1=C(C#CC2=CN=C3N2C=CN=C3)C=CC=C1NC(NC4=CC(C(C)(C)C)=NN4C5=CC=CC=C5)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)