Tyrosinase-IN-7
Based on 1 Customer Validation
Tyrosinase-IN-7 is a potent tyrosinase inhibitor with an IC50 value of 1.57 µM. Tyrosinase-IN-7 inhibits cell growth with low cytotoxicity.
For research use only. We do not sell to patients.
- Purity: 99.66%
- CAS No.: 2873418-52-9
- Formula: C15H10O5
- Molecular Weight:270.24
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
IC50: 1.57 µM (Tyrosinase)[1]
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| MNT-1 | CC50 |
108 μM
Compound: 10
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Cytotoxicity against human MNT-1 cells
Cytotoxicity against human MNT-1 cells
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[PMID: 36462443] |
| MNT-1 | IC50 |
32 μM
Compound: 10
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Inhibition of melanogenesis in human MNT-1 cells incubated for 96 hrs
Inhibition of melanogenesis in human MNT-1 cells incubated for 96 hrs
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[PMID: 36462443] |
Tyrosinase-IN-7 (compound 10) shows cytotoxicity with an IC50 value of 32 µM, an CC50 value of 108 µM in MNT-1 whole cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2873418-52-9
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Appearance Solid
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Molecular Weight 270.24
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Formula C15H10O5
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Color Orange to red
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SMILES
OC(C=CC=C1C/2=O)=C1OC2=C/C3=CC=C(C=C3O)O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (370.04 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (275 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.7004 mL | 18.5021 mL | 37.0041 mL | 92.5104 mL |
| 5 mM | 0.7401 mL | 3.7004 mL | 7.4008 mL | 18.5021 mL | |
| 10 mM | 0.3700 mL | 1.8502 mL | 3.7004 mL | 9.2510 mL | |
| 15 mM | 0.2467 mL | 1.2335 mL | 2.4669 mL | 6.1674 mL | |
| 20 mM | 0.1850 mL | 0.9251 mL | 1.8502 mL | 4.6255 mL | |
| 25 mM | 0.1480 mL | 0.7401 mL | 1.4802 mL | 3.7004 mL | |
| 30 mM | 0.1233 mL | 0.6167 mL | 1.2335 mL | 3.0837 mL | |
| 40 mM | 0.0925 mL | 0.4626 mL | 0.9251 mL | 2.3128 mL | |
| 50 mM | 0.0740 mL | 0.3700 mL | 0.7401 mL | 1.8502 mL | |
| 60 mM | 0.0617 mL | 0.3084 mL | 0.6167 mL | 1.5418 mL | |
| 80 mM | 0.0463 mL | 0.2313 mL | 0.4626 mL | 1.1564 mL | |
| 100 mM | 0.0370 mL | 0.1850 mL | 0.3700 mL | 0.9251 mL |
Tyrosinase-IN-7 Related Classifications
HY-151977 Related Classifications
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