UK‑396082
Based on 1 Customer Validation
UK‑396082 is a potent thrombin activated fibrinolytic inhibitor (TAFI) inhibitor. UK‑396082 increases plasmin activity and induces a parallel decrease in ECM levels. UK‑396082 can be used in research of chronic kidney disease (CKD).
For research use only. We do not sell to patients.
- Purity: 99.89%
- CAS No.: 400044-47-5
- Formula: C12H21N3O2
- Molecular Weight:239.31
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
UK‑396082 (0-1000 nM; NRK52E cells; 96 h) induces TAFI activity in a dose-dependent manner[1].
UK‑396082 (500 nM; 24 h) increases plasmin activity in NRK52E cells (+109%) and NRK49F fibroblasts (+38.3%)[1].
UK‑396082 (500 nM; 24 h) has a 46% reduction in ECM levels[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 400044-47-5
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Appearance Solid
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Molecular Weight 239.31
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Formula C12H21N3O2
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Color white
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SMILES
CCCN1C=C(C[C@@H](C(O)=O)CCCN)N=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Purity & Documentation
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Data Sheet (266 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)