VEGFR-IN-5
VEGFR-IN-5 (compound 9k) is a potent inhibitor of VEGFR2, with the IC50 of 8.4 nM and an acceptable oral bioavailability. VEGFR-IN-5 inhibits migration and invasion of human umbilical vein endothelial cells (HUVEC) cells and induces apoptosis.
For research use only. We do not sell to patients.
- Formula: C31H28ClF3N6O2
- Molecular Weight:609.04
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All VEGFR Isoforms
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Biological Activity
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VEGFR2 8.4 nM (IC50) |
Chemical Information
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Molecular Weight 609.04
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Formula C31H28ClF3N6O2
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SMILES
COC1=CC2=CC=C(C=C2C=C1C(NC3=CC=C(C(C(F)(F)F)=C3)CN4CCN(CC4)C)=O)C5=CN=C6C=CC(Cl)=NN56
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)