WYZ90
WYZ90 ((compound 6a) is a potent and selective COX-2 inhibitor with IC50 values of 75, 5734, 19940 nM for COX-2, COX-1 and DPPH, respectively. WYZ90 shows antioxidant and analgesic activity.
For research use only. We do not sell to patients.
- CAS No.: 3040313-48-9
- Formula: C18H17N3O3
- Molecular Weight:323.35
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
IC50 & Target
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COX-2 75 nM (IC50) |
COX-1 5734 nM (IC50) |
Chemical Information
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CAS No. 3040313-48-9
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Molecular Weight 323.35
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Formula C18H17N3O3
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SMILES
O=C1C(CC2=CC=C(C(NO)=O)C=C2)=C(C)NN1C3=CC=CC=C3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)