XOR/URAT1-IN-1
XOR/URAT1-IN-1 (Compound II15) is a dual inhibitor for xanthine oxidoreductase (XOR) and uric acid transporter 1 (URAT1), with IC50 of 6 nM and 12.9 μM. XOR/URAT1-IN-1 lowers the levels of uric acid in Potassium oxonate (HY-17511)/Hypoxanthine (HY-N0091)-induced acute hyperuricemia mouse model.
For research use only. We do not sell to patients.
- CAS No.: 2810137-86-9
- Formula: C18H13ClN2O3
- Molecular Weight:340.76
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
IC50: 6 nM (XOR), 12.9 μM (URAT1)
Chemical Information
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CAS No. 2810137-86-9
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Molecular Weight 340.76
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Formula C18H13ClN2O3
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SMILES
O=C(O)C1=CC=C(C=C1O)C2=CC(NC3=CC=CC(Cl)=C3)=CN=C2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)