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Cat. No.: HY-148806

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Zatonacaftor

Zatonacaftor is a modulator of cystic fibrosis transmembrane regulator (CFTR) protein. Zatonacaftor can be used for research of cystic fibrosis.

For research use only. We do not sell to patients.

CAS No.: 2301945-38-8
Formula: C₂₄H₂₇N₃O₄S
Molecular Weight:453.55

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (273 KB)

Zatonacaftor Chemical Structure

CAS No.: 2301945-38-8

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

Zatonacaftor is a modulator of cystic fibrosis transmembrane regulator (CFTR) protein. Zatonacaftor can be used for research of cystic fibrosis^[1]^[2].

Chemical Information

CAS No. 2301945-38-8
Molecular Weight 453.55
Formula C₂₄H₂₇N₃O₄S
SMILES

O=C(C1(CC1)C2=CC(CC)=CN=C2OC(C)C)NS(=O)(C3=C4C=CC(C)=NC4=CC=C3)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (273 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Altenbach Robert J, et al. Preparation of substituted N-sulfonylcyclopropanecarboxamides as modulators of the cystic fibrosis transmembrane conductance regulator protein: United States, US20190077784. 2019-03-14.

[2]. WHO Drug Information-World Health Organization (WHO).

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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