ZER1 binder-1
ZER1 binder-1 is a pyridazinone derivative and a binding agent for the E3 ubiquitin ligase ZER1, with an FP EC50 value of 55.59 nM. ZER1 binder-1 is applicable to the research of cancers induced by human papillomavirus (HPV) infection.
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- CAS No.: 3132618-21-1
- Formule: C21H18ClN7O2
- Masse moléculaire:435.87
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
- Protocole
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
Description
IC50 & Target
[1]|
ZER1 (469-766) 55.59 nM (EC50) |
In Vitro
Chemical Information
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CAS No. 3132618-21-1
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Masse moléculaire 435.87
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Formule C21H18ClN7O2
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SMILES
O=C1N(N=CC=C1C2=CC([C@@H](N)C)=NO2)C3=CC(C4=CN(N=C4)C(C)C#N)=CC(Cl)=C3
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocole
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Research Protocol for Infectious Diseases
Infectious-disease experiments test how pathogens interact with host barriers, innate immune receptors, inflammatory signaling, pathogen replication, and tissue injury; pattern-recognition receptors such as TLRs, RIG-I-like receptors, NOD-like receptors, and inflammasomes detect microbial molecules and activate NF-κB, interferon, and cytokine responses. The central hypothesis is that infection severity reflects the balance between pathogen burden and host response: protective inflammation restricts pathogen growth, whereas excessive or mislocalized inflammation contributes to tissue damage and disease phenotype. Unresolved questions include which host pathways are protective versus pathogenic, why some infection models fail to translate to human disease, and which combined readouts best predict clinically relevant infection outcomes.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
ZER1 binder-1 Related Classifications
HY-185878 Related Classifications
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