β-Glucuronidase responsive conjugate 1
β-Glucuronidase responsive conjugate 1 (compound 3) is a well-balanced photosensitizer which has photodynamic activity. β-Glucuronidase responsive conjugate 1 inhibits T-24 cell viability and growth with an IC50 of 0.2 μM. β-Glucuronidase responsive conjugate 1 can used to study bladder cancers.
For research use only. We do not sell to patients.
- Formula: C108H127FN16O34Zn
- Molecular Weight:2277.63
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
β-Glucuronidase responsive conjugate 1 (0.01 μM, 24 h) inhibits cell viability in T-24 cells [1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:T-24 cells
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Concentration:1 nM-100 μM
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Incubation Time:24 hours
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Result:Pronouncedly reduced cell viability when treated with 0.01 μM.
Inhibited tumor growth in 3D in vitro model.
Chemical Information
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Molecular Weight 2277.63
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Formula C108H127FN16O34Zn
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SMILES
O=C(C1(CC1)C(NC2=CC=C(OC3=CC=NC4=CC(OCCOC(N(C)CCN(C(OCC5=CC=C(O[C@@H]6O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]6O)C=C5NC(CCC(NCCOCCOCCNC(C7=C(C)C8=CC9=[N]%10[Zn]%11%12N8C7=C(CC(OC)=O)C([C@@H](CCC(NCC%13=CN([C@H]%14[C@H](O)[C@@H](O)[C@H](O[C@H]%15O[C@H](CO)[C@@H](O)[C@H](O)[C@H]%15O)[C@@H](CO)O%14)N=N%13)=O)[C@@H]%16C)=[N]%11C%16=CC%17=C(C)C(C=C)=C(N%17%12)C=C%10C(C)=C9CC)=O)=O)=O)=O)C)=O)=C(OC)C=C34)C=C2)=O)NC%18=CC=C(F)C=C%18
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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