1-Phenyl-1H-benzimidazole-6-carboxylic acid
1-Phenyl-1H-benzimidazole-6-carboxylic acid is a PDGF inhibitor.
For research use only. We do not sell to patients.
- CAS No.: 220495-76-1
- Formula: C14H10N2O2
- Molecular Weight:238.25
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| Sf9 | IC50 |
50 μM
Compound: 79
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Inhibition of phosphorylation of a random glutamate/tyrosine copolymer in lysates of transfected Sf9 insect cells overexpressing human fibroblast growth factor receptor 1
Inhibition of phosphorylation of a random glutamate/tyrosine copolymer in lysates of transfected Sf9 insect cells overexpressing human fibroblast growth factor receptor 1
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[PMID: 9876115] |
In Vitro
1-Phenyl-1H-benzimidazole-6-carboxylic acid (Compound 33) inhibits platelet-derived growth factor, with an experimental log (1/IC50) value of 4.30. Moreover, the GA-ANN QSAR model accurately predicts this activity, yielding a calculated log (1/IC50) value of 4.49[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
Chemical Information
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CAS No. 220495-76-1
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Molecular Weight 238.25
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Formula C14H10N2O2
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SMILES
O=C(O)C=1C=CC=2N=CN(C=3C=CC=CC3)C2C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
1-Phenyl-1H-benzimidazole-6-carboxylic acid Related Classifications
HY-187149 Related Classifications
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