15(S)-Latanoprost
15(S)-Latanoprost is an analog of latanoprost in which the hydroxyl at carbon 15 is inverted relative to latanoprost. The IC50 values for the free acid forms of latanoprost and 15(S)-latanoprost were determined to be 3.6 nM and 24 nM, respectively, in a FP receptor binding assay using the cat iris sphincter muscle. A 3 μg dose of 15(S)-latanoprost caused a 1 mmHg reduction of IOP in normotensive cynomolgus monkeys.
For research use only. We do not sell to patients.
- CAS No.: 145773-22-4
- Formula: C26H40O5
- Molecular Weight:432.59
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
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HY-126115R
15(S)-Latanoprost (Standard) -
HY-B0600
TafluprostProstaglandin Receptor Agonist -
HY-113756A
Latanoprost acidFP Agonist -
HY-B0191
BimatoprostProstaglandin Analog -
HY-B0601
Tafluprost acidFP Receptor Agonist -
HY-B0584A
5,6-trans-TravoprostIsomer -
HY-130395
15-Keto latanoprostLatanoprost Metabolite -
HY-108560
(+)-FluprostenolPTGER2 Agonist -
HY-B0600R
Tafluprost (Standard)Prostaglandin Receptor Agonist -
HY-116617
15-Keto TravoprostTravoprost Metabolite -
HY-132277
15-Keto BimatoprostPGF2α Analog -
HY-113756AR
Latanoprost acid (Standard)Selective FP Agonist
Biological Activity
Description
Chemical Information
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CAS No. 145773-22-4
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Molecular Weight 432.59
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Formula C26H40O5
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SMILES
O[C@@H]1[C@@H]([C@H]([C@@H](C1)O)CC[C@@H](CCC2=CC=CC=C2)O)C/C=C\CCCC(OC(C)C)=O
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Synonyms
15-epi Latanoprost
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
15(S)-Latanoprost Related Classifications
HY-126115 Related Classifications
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