2. GPCR/G Protein
  3. Prostaglandin Receptor
  4. 17-Phenyl trinor prostaglandin E2 ethyl amide

17-Phenyl trinor prostaglandin E2 ethyl amide  (Synonyms: 17-Phenyl trinor PGE2 ethyl amide)

Cat. No.: HY-138868
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17-Phenyl trinor prostaglandin E2 ethyl amide (17-Phenyl trinor PGE2 ethyl amide) is a EP1 receptor agonist. 17-Phenyl trinor prostaglandin E2 ethyl amide aggravates renal dysfunction and glomerulosclerosis.

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17-Phenyl trinor prostaglandin E2 ethyl amide Chemical Structure

17-Phenyl trinor prostaglandin E2 ethyl amide Chemical Structure

CAS No. : 1219032-20-8

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17-Phenyl trinor prostaglandin E2 ethyl amide Related Antibodies

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Description

17-Phenyl trinor prostaglandin E2 ethyl amide (17-Phenyl trinor PGE2 ethyl amide) is a EP1 receptor agonist. 17-Phenyl trinor prostaglandin E2 ethyl amide aggravates renal dysfunction and glomerulosclerosis[1].

In Vivo

17-Phenyl trinor prostaglandin E2 ethyl amide (0.3 µg/g; i.p.; three times a week for 12 weeks) aggravates renal dysfunction and glomerulosclerosis in five‑sixths nephrectomy renal fibrosis model mice[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: 8-12 weeks, 15-20 g, C57/BL6 male mice (five‑sixths nephrectomy renal fibrosis model)[1]
Dosage: 0.3 µg/g
Administration: I.p.; three times a week for 12 weeks
Result: Increased the plasma blood urea nitrogen (BUN) levels and plasma creatinine (Cr) concentration, increased the extracellular matrix and the area of collagen deposition, upregulated the protein of expression of Col1, GRP78, TRPC1 and PERK in 5/6 Nx mice.
Molecular Weight

413.55

Formula

C25H35NO4
CAS No.
SMILES

O[C@@H](CCC1=CC=CC=C1)/C=C/[C@@H]2[C@H](C(C[C@H]2O)=O)C/C=C\CCCC(NCC)=O
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Room temperature in continental US; may vary elsewhere.
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Please store the product under the recommended conditions in the Certificate of Analysis.
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17-Phenyl trinor prostaglandin E2 ethyl amide Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

17-Phenyl trinor prostaglandin E2 ethyl amide1219032-20-817-Phenyl trinor PGE2 ethyl amideProstaglandin ReceptorCol1GRP78TRPC1PERKglomerulosclerosisInhibitorinhibitorinhibit

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