17-Phenyl trinor prostaglandin E2 ethyl amide
17-Phenyl trinor prostaglandin E2 ethyl amide (17-Phenyl trinor PGE2 ethyl amide) is a EP1 receptor agonist. 17-Phenyl trinor prostaglandin E2 ethyl amide aggravates renal dysfunction and glomerulosclerosis.
For research use only. We do not sell to patients.
- CAS No.: 1219032-20-8
- Formula: C25H35NO4
- Molecular Weight:413.55
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:8-12 weeks, 15-20 g, C57/BL6 male mice (five‑sixths nephrectomy renal fibrosis model)[1]
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Dosage:0.3 µg/g
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Administration:I.p.; three times a week for 12 weeks
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Result:Increased the plasma blood urea nitrogen (BUN) levels and plasma creatinine (Cr) concentration, increased the extracellular matrix and the area of collagen deposition, upregulated the protein of expression of Col1, GRP78, TRPC1 and PERK in 5/6 Nx mice.
Chemical Information
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CAS No. 1219032-20-8
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Molecular Weight 413.55
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Formula C25H35NO4
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SMILES
O[C@@H](CCC1=CC=CC=C1)/C=C/[C@@H]2[C@H](C(C[C@H]2O)=O)C/C=C\CCCC(NCC)=O
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Synonyms
17-Phenyl trinor PGE2 ethyl amide
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)