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Cat. No.: HY-164137

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17β-HSD5 inhibitor 2

17β-HSD5 inhibitor 2 (Compound 30) is an inhibitor for 17β-hydroxysteroid dehydrogenases 5 (17β-HSD 5) with IC₅₀ of 40 nM.

For research use only. We do not sell to patients.

CAS No.: 1106941-19-8
Formula: C₂₂H₁₆F₃N₃O₂
Molecular Weight:411.38

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

17β-HSD5 inhibitor 2 Chemical Structure

CAS No.: 1106941-19-8

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Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Bioz

Biological Activity

Description

17β-HSD5 inhibitor 2 (Compound 30) is an inhibitor for 17β-hydroxysteroid dehydrogenases 5 (17β-HSD 5) with IC₅₀ of 40 nM^[1].

IC₅₀ & Target

17β-HSD5

40 nM (IC₅₀)

All 17β-HSD Isoforms :

17β-HSD5/AKR1C3

Chemical Information

CAS No. 1106941-19-8
Molecular Weight 411.38
Formula C₂₂H₁₆F₃N₃O₂
SMILES

FC(F)(F)C1=CC2=C(N(C3=CC=CC(C(OCC)=O)=C3)C(C4=CC=NC=C4)=N2)C=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Marchais-Oberwinkler S, et al., 17β-Hydroxysteroid dehydrogenases (17β-HSDs) as therapeutic targets: protein structures, functions, and recent progress in inhibitor development. J Steroid Biochem Mol Biol. 2011 May;125(1-2):66-82. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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