2-Hydroxybenzimidazole (Standard)
2-Hydroxybenzimidazole (Standard) is the analytical standard of 2-Hydroxybenzimidazole (HY-W008003). This product is intended for research and analytical applications. 2-Hydroxybenzimidazole is a metabolite of Carbendazim (HY-13582). 2-Hydroxybenzimidazole is produced by the degradation of Carbendazim (HY-13582) by mycobacteria. 2-Hydroxybenzimidazole does not induce CYP1A1 protein expression and does not significantly reduce mortality in mice after influenza virus challenge following intranasal administration. 2-Hydroxybenzimidazole can be used in research on tobacco mosaic virus infection and influenza.
For research use only. We do not sell to patients.
- Purity : 98%
- CAS No.: 615-16-7
- Formula: C7H6N2O
- Molecular Weight:134.14
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Product Information
Information
Application
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
-
CAS No. 615-16-7
-
Molecular Weight 134.14
-
Formula C7H6N2O
-
SMILES
O=C1NC2=CC=CC=C2N1
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[3]. Bai N, et al. Rhamnolipid-aided biodegradation of carbendazim by Rhodococcus sp. D-1: Characteristics, products, and phytotoxicity. Science of the Total Environment. 2017 Jul 15;590:343-51. [Content Brief]
[5]. Yang Y, et al. Effects of superabsorbent polymers on the fate of fungicidal carbendazim in soils. Journal of hazardous materials. 2017 Apr 15;328:70-79. [Content Brief]
[6]. Wang Z, et al. Biodegradation of carbendazim by a novel actinobacterium Rhodococcus jialingiae djl-6-2. Chemosphere. 2010 Oct;81(5):639-44. [Content Brief]
[7]. Zhang X, et al. Isolation and characterization of carbendazim-degrading Rhodococcus erythropolis djl-11. PloS one. 2013;8(10):e74810. [Content Brief]
[8]. Backlund M, et al. Structural and mechanistic aspects of transcriptional induction of cytochrome P450 1A1 by benzimidazole derivatives in rat hepatoma H4IIE cells. European Journal of Biochemistry. 1999 Mar 19;261(1):66-71. [Content Brief]
[9]. Takano K, et al. Nucleic acid-induced resistance to viral infection. Journal of Bacteriology. 1965 Dec;90(6):1542-7. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Keywords
- 2-Hydroxybenzimidazole (Standard)
- 615-16-7
- Reference Standards
- Drug Metabolite
- Bacterial
- Mycobacterium sp. SD-4
- influenza virus
- Rhodococcus jialingiae djl-6-2
- rat hepatoma cells
- tobacco mosaic virus
- soya bean callus
- RNA-dependent RNA polymerase
- amaranthus betacyanin
- tomato leaf discs
- encephalomyocarditis virus
- Inhibitor
- inhibitor
- inhibit