3′-Deoxy-3′-fluorouridine
Based on 1 Customer Validation
3′-Deoxy-3′-fluorouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
For research use only. We do not sell to patients.
- Purity: 99.66%
- CAS No.: 57944-13-5
- Formula: C9H11FN2O5
- Molecular Weight:246.19
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| L1210 | IC50 |
>100 μg/mL
Compound: 23
|
Concentration required to reduce the viability of Murine leukemia L1210 cells
Concentration required to reduce the viability of Murine leukemia L1210 cells
|
[PMID: 2066992] |
| MOLT-4F | IC50 |
>100 μg/mL
Compound: 23
|
Concentration required to reduce the viability of Human T-lymphoblast Molt/4F cells
Concentration required to reduce the viability of Human T-lymphoblast Molt/4F cells
|
[PMID: 2066992] |
| MT4 | IC50 |
6.9 μg/mL
Compound: 23
|
Concentration required to reduce the viability of Human T-lymphoblast MT-4 cells
Concentration required to reduce the viability of Human T-lymphoblast MT-4 cells
|
[PMID: 2066992] |
| Raji | IC50 |
>100 μg/mL
Compound: 23
|
Concentration required to reduce the viability of Human B-lymphoblast Raji cells
Concentration required to reduce the viability of Human B-lymphoblast Raji cells
|
[PMID: 2066992] |
Chemical Information
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CAS No. 57944-13-5
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Appearance Solid
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Molecular Weight 246.19
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Formula C9H11FN2O5
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Color White to off-white
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SMILES
O[C@@H]1[C@H](F)[C@@H](CO)O[C@H]1N2C(NC(C=C2)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Purity & Documentation
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Data Sheet (269 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)