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3-O-Methyltolcapone (Standard)

(Synonyms: Ro 40-7591 (Standard))

3-O-Methyltolcapone (Standard) (Ro 40-7591 (Standard)) is the analytical standard of 3-O-Methyltolcapone (HY-174062). 3-O-Methyltolcapone (Ro 40-7591) is a metabolite of Tolcapone (HY-17406). Tolcapone (Ro 40-7592) is a selective, potent and orally active COMT inhibitor with an IC50of 773 nM. Tolcapone can inhibits α-syn and Aβ42 oligomerization and fibrillogenesis. Tolcapone can cause oxidative stress and induce cancer cells apoptosis and ROS production. Tolcapone can be used for the researches of cancer and neurological disease, such as Parkinson disease and neuroblastoma.

For research use only. We do not sell to patients.

  • CAS No.: 134612-80-9
  • Formula: C15H13NO5
  • Molecular Weight:287.27
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • 3-O-Methyltolcapone (Standard) Chemical Structure
    3-O-Methyltolcapone (Standard) Chemical Structure
CAS No.: 134612-80-9
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    3-O-Methyltolcapone (Standard) Chemical Structure
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  • 3-O-Methyltolcapone (Standard)