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Cat. No.: HY-W782032B

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3D-Monophosphoryl Lipid A-5 triethylamine

Name: 3D-Monophosphoryl Lipid A-5 triethylamine
Brand: MedChemExpress
SKU: HY-W782032B
Availability: PreOrder

(Synonyms: 3D-MPLA-5 triethylamine)

1 Cited Publications

Customer Review

Based on 1 publication(s) in Google Scholar

3D-Monophosphoryl Lipid A-5 (3D-MPLA-5) triethylamine is a TLR agonist that can be used as an adjuvant for vaccines to enhance their immunogenicity.

For research use only. We do not sell to patients.

Formula: C₈₈H₁₇₀N₃O₂₀P
Molecular Weight:1621.27

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

3D-Monophosphoryl Lipid A-5 triethylamine Chemical Structure

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Publications (1)
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
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Biological Activity

Description

3D-Monophosphoryl Lipid A-5 (3D-MPLA-5) triethylamine is a TLR agonist that can be used as an adjuvant for vaccines to enhance their immunogenicity^[1].

All Toll-like Receptor (TLR) Isoforms :

In Vitro

Monophosphoryl Lipid A (MPLA) is a low-toxicity derivative of lipopolysaccharide (LPS) that retains the immunologically active lipid A portion of the parent molecule. Both LPS and MPLA are TLR4 agonists, but they signal through different adaptors, MyD88 and TRIF, respectively.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

Molecular Weight 1621.27
Formula C₈₈H₁₇₀N₃O₂₀P
SMILES

CCCCCCCCCCCCCC(O[C@H](CCCCCCCCCCC)CC(N[C@@H]1[C@H]([C@@H]([C@H](O[C@H]1OC[C@@H]2[C@H]([C@@H]([C@H]([C@H](O2)O)NC(C[C@H](O)CCCCCCCCCCC)=O)O)O)CO)OP(O)(O)=O)OC(C[C@@H](CCCCCCCCCCC)OC(CCCCCCCCCCCCC)=O)=O)=O)=O.CCN(CC)CC
Synonyms

3D-MPLA-5 triethylamine
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Publications (1)

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Sci Rep

BMSC-derived exosomal ANTXR1 inhibits erythroid differentiation by suppressing the TLR4/MyD88/NF-κB signaling pathway. [Abstract]

2026 Apr 16;16(1):19999. PMID: 41992002

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Rollman E, et al. Evaluation of immunogenicity and efficacy of combined DNA and adjuvanted protein vaccination in a human immunodeficiency virus type 1/murine leukemia virus pseudotype challenge model[J]. Vaccine, 2007, 25(11): 2145-2154. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Keywords

3D-Monophosphoryl Lipid A-5 triethylamine

1 Cited Publications

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Biological Activity
- Description
- In Vitro
Chemical Information
Publications (1)
Purity & Documentation
References

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3D-Monophosphoryl Lipid A-5 triethylamine

Publications Citing Use of MedChemExpress (MCE) 3D-Monophosphoryl Lipid A-5 triethylamine

All Toll-like Receptor (TLR) Isoforms

Biological Activity

Chemical Information

Publications (1)

Purity & Documentation

References

Calculators

Help & FAQs

3D-Monophosphoryl Lipid A-5 triethylamine Related Classifications

HY-W782032B Related Classifications

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