3β,7β,15α-Trihydroxy-4-(hydroxymethyl)-11,23-dioxo-lanost-8-en-26-oic acid
3β,7β,15α-Trihydroxy-4-(hydroxymethyl)-11,23-dioxo-lanost-8-en-26-oic acid is a triterpene compound that can be found in Ganoderma lucidum, and it inhibits nitric oxide (NO) production in BV-2 microglial cells induced by lipopolysaccharide (LPS, HY-D1056), with an IC50 of 4.15 μM.
For research use only. We do not sell to patients.
- CAS No.: 1961358-03-1
- Formula: C30H46O8
- Molecular Weight:534.68
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Protocols
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
Description
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| BV-2 | IC50 |
4.15 μM
Compound: 5
|
Antiinflammatory activity in mouse BV2 cells assessed as inhibition of LPS-induced NO production incubated for 24 hrs measured after 15 mins by Griess assay
Antiinflammatory activity in mouse BV2 cells assessed as inhibition of LPS-induced NO production incubated for 24 hrs measured after 15 mins by Griess assay
|
[PMID: 27335254] |
Chemical Information
-
CAS No. 1961358-03-1
-
Molecular Weight 534.68
-
Formula C30H46O8
-
SMILES
C[C@]12C3=C(C(C[C@@]1([C@@](C[C@@H]2O)([H])[C@H](C)CC(CC(C)C(O)=O)=O)C)=O)[C@@]4([C@@]([C@@](C)([C@H](CC4)O)CO)([H])C[C@@H]3O)C
-
Structure Classification
-
Initial Source
Ganoderma curtisii
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
-
Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
3β,7β,15α-Trihydroxy-4-(hydroxymethyl)-11,23-dioxo-lanost-8-en-26-oic acid Related Classifications
HY-N13701 Related Classifications
Powered by Bioz