5-LOX-IN-1
Based on 1 Customer Validation
5-LOX-IN-1 (compound 2b) is an inhibitor of human 5-Lipoxygenase (5-LOX) with an IC50 value of 2.3 μM. 5-LOX-IN-1 can be used for the research of inflammation.
For research use only. We do not sell to patients.
- Purity: 98.04%
- CAS No.: 55040-82-9
- Formula: C20H18N2O2S
- Molecular Weight:350.43
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
IC50: 2.3 μM (5-LOX)[1]
Chemical Information
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CAS No. 55040-82-9
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Appearance Solid
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Molecular Weight 350.43
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Formula C20H18N2O2S
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Color Light yellow to yellow
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SMILES
O=C(C1=C(C2=CC=CC=C2)N=C(N3CCOCC3)S1)C4=CC=CC=C4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (285.36 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (277 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.8536 mL | 14.2682 mL | 28.5364 mL | 71.3409 mL |
| 5 mM | 0.5707 mL | 2.8536 mL | 5.7073 mL | 14.2682 mL | |
| 10 mM | 0.2854 mL | 1.4268 mL | 2.8536 mL | 7.1341 mL | |
| 15 mM | 0.1902 mL | 0.9512 mL | 1.9024 mL | 4.7561 mL | |
| 20 mM | 0.1427 mL | 0.7134 mL | 1.4268 mL | 3.5670 mL | |
| 25 mM | 0.1141 mL | 0.5707 mL | 1.1415 mL | 2.8536 mL | |
| 30 mM | 0.0951 mL | 0.4756 mL | 0.9512 mL | 2.3780 mL | |
| 40 mM | 0.0713 mL | 0.3567 mL | 0.7134 mL | 1.7835 mL | |
| 50 mM | 0.0571 mL | 0.2854 mL | 0.5707 mL | 1.4268 mL | |
| 60 mM | 0.0476 mL | 0.2378 mL | 0.4756 mL | 1.1890 mL | |
| 80 mM | 0.0357 mL | 0.1784 mL | 0.3567 mL | 0.8918 mL | |
| 100 mM | 0.0285 mL | 0.1427 mL | 0.2854 mL | 0.7134 mL |