5-n-Tricosylresorcinol
5-n-Tricosylresorcinolthe is the first cyst lipid. 5-n-Tricosylresorcinolthe has metahydroxyl group which allows it to self-associate forming a staggered-chain conformation in which the polar head groups have heaxagonal symmetry. 5-n-Tricosylresorcinolthe reduces hydrogen peroxide-induced DNA damage.
For research use only. We do not sell to patients.
- CAS No.: 70110-60-0
- Formula: C29H52O2
- Molecular Weight:432.72
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All DNA/RNA Synthesis Isoforms
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Biological Activity
Description
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HCT-116 | IC50 |
>50 μg/mL
Compound: 12
|
Growth inhibition of human HCT116 cells after 48 hrs by MTT assay
Growth inhibition of human HCT116 cells after 48 hrs by MTT assay
|
[PMID: 21658963] |
| HT-29 | IC50 |
>50 μg/mL
Compound: 12
|
Growth inhibition of human HT-29 cells after 48 hrs by MTT assay
Growth inhibition of human HT-29 cells after 48 hrs by MTT assay
|
[PMID: 21658963] |
Chemical Information
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CAS No. 70110-60-0
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Molecular Weight 432.72
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Formula C29H52O2
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SMILES
OC1=CC(CCCCCCCCCCCCCCCCCCCCCCC)=CC(O)=C1
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Structure Classification
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Initial Source
Azotobacter vinelandii
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Genotoxicity/Mutagenicity Study
The bacterial reverse mutation assay detects point mutations that restore amino-acid prototrophy in auxotrophic Salmonella typhimurium or Escherichia coli tester strains; after exposure to a test article, mutagenic activity is read out as an increased number of revertant colonies on minimal agar compared with the vehicle control. The assay uses tester strains with different mutation targets so that base-substitution and frameshift mutagens can be detected, and testing is performed with and without exogenous mammalian metabolic activation because some chemicals require biotransformation to become mutagenic.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)