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Cat. No.: HY-19146

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CL-275838

CL-275838 is a memory-enhancing agent, also with potent antidepressant activities.

For research use only. We do not sell to patients.

CAS No.: 115931-65-2
Formula: C₂₇H₂₅F₃N₆O
Molecular Weight:506.52

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

CL-275838 Chemical Structure

CAS No.: 115931-65-2

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vivo
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

CL-275838 is a memory-enhancing agent, also with potent antidepressant activities.

In Vivo

CL 275,838 metabolism has sex-dependent differences in rat. CL 275,838 does not appreciably affect its own oxidation or cause significant hepatic microsomal enzyme induction in the male or female rat, except for slight enhancement of some components of the P450 system at doses (300?mg/kg once daily for 7 days) well above the effective pharmacological range^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 115931-65-2
Molecular Weight 506.52
Formula C₂₇H₂₅F₃N₆O
SMILES

N#CC1=C2N(C(CN3CCN(CC4=CC=CC=C4)CC3)=O)CC=C(C5=CC=CC(C(F)(F)F)=C5)N2N=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Ferrarese A, et al. Hepatic microsomal metabolism of the potential memory-enhancing agent, CL 275,838, to its desbenzyl derivative. Xenobiotica. 1993 Sep;23(9):1007-16. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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