1. Others
  2. Others
  3. Fabomotizole hydrochloride

Fabomotizole hydrochloride  (Synonyms: CM346 hydrochloride)

Cat. No.: HY-14895A Purity: 99.95%
COA Handling Instructions

Fabomotizole hydrochloride (CM346 hydrochloride) is an anxiolytic agent. Fabomotizole hydrochloride produces anxiolytic and neuroprotective effects without any muscle relaxant actions.

For research use only. We do not sell to patients.

Fabomotizole hydrochloride Chemical Structure

Fabomotizole hydrochloride Chemical Structure

CAS No. : 173352-39-1

Size Price Stock Quantity
Free Sample (0.1 - 0.5 mg)   Apply Now  
Solid + Solvent
10 mM * 1 mL in DMSO
ready for reconstitution
USD 154 In-stock
Solution
10 mM * 1 mL in DMSO USD 154 In-stock
Solid
5 mg USD 140 In-stock
10 mg USD 230 In-stock
50 mg USD 800 In-stock
100 mg USD 1280 In-stock
200 mg   Get quote  
500 mg   Get quote  

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Other Forms of Fabomotizole hydrochloride:

Top Publications Citing Use of Products
  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Fabomotizole hydrochloride (CM346 hydrochloride) is an anxiolytic agent. Fabomotizole hydrochloride produces anxiolytic and neuroprotective effects without any muscle relaxant actions.

In Vitro

Afobazole's mechanism of action remains poorly defined however, with GABAergic, NGF and BDNF release promoting, MT1 receptor antagonism, MT3 receptor antagonism, and sigma agonism suggested as potential mechanisms. Afobazole was shown to inhibit MAO-A reversibly and there might be also some involvement with serotonin receptors. Afobazole has found little clinical use outside of Russia and has not been evaluated by the FDA.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

343.87

Formula

C15H22ClN3O2S

CAS No.
Appearance

Solid

Color

Light yellow to yellow

SMILES

CCOC1=CC=C2C(N=C(SCCN3CCOCC3)N2)=C1.Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : 100 mg/mL (290.81 mM; Need ultrasonic)

DMSO : ≥ 44 mg/mL (127.96 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.9081 mL 14.5404 mL 29.0808 mL
5 mM 0.5816 mL 2.9081 mL 5.8162 mL
10 mM 0.2908 mL 1.4540 mL 2.9081 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  PBS

    Solubility: 50 mg/mL (145.40 mM); Clear solution; Need ultrasonic

*All of the co-solvents are available by MedChemExpress (MCE).
Purity & Documentation
References
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.

Fabomotizole hydrochloride Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

 

Salutation

Applicant Name *

 

Email Address *

Phone Number *

 

Organization Name *

Department *

 

Requested quantity *

Country or Region *

     

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
Fabomotizole hydrochloride
Cat. No.:
HY-14895A
Quantity:
MCE Japan Authorized Agent: