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Fabomotizole hydrochloride (Synonyms: CM346 hydrochloride)

Cat. No.: HY-14895A Purity: 99.77%
Handling Instructions

Fabomotizole hydrochloride (CM346 hydrochloride) is an anxiolytic drug. Fabomotizole hydrochloride produces anxiolytic and neuroprotective effects without any muscle relaxant actions.

For research use only. We do not sell to patients.

Fabomotizole hydrochloride Chemical Structure

Fabomotizole hydrochloride Chemical Structure

CAS No. : 173352-39-1

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Solution
10 mM * 1 mL in DMSO USD 182 In-stock
Estimated Time of Arrival: December 31
Solid + Solvent
10 mM * 1 mL
ready for reconstitution
USD 182 In-stock
Estimated Time of Arrival: December 31
Solid
5 mg USD 165 In-stock
Estimated Time of Arrival: December 31
10 mg USD 275 In-stock
Estimated Time of Arrival: December 31
50 mg USD 935 In-stock
Estimated Time of Arrival: December 31
100 mg USD 1595 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
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Other Forms of Fabomotizole hydrochloride:

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Description

Fabomotizole hydrochloride (CM346 hydrochloride) is an anxiolytic drug. Fabomotizole hydrochloride produces anxiolytic and neuroprotective effects without any muscle relaxant actions.

In Vitro

Afobazole's mechanism of action remains poorly defined however, with GABAergic, NGF and BDNF release promoting, MT1 receptor antagonism, MT3 receptor antagonism, and sigma agonism suggested as potential mechanisms. Afobazole was shown to inhibit MAO-A reversibly and there might be also some involvement with serotonin receptors. Afobazole has found little clinical use outside of Russia and has not been evaluated by the FDA.

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

343.87

Formula

C15H22ClN3O2S

CAS No.
SMILES

CCOC1=CC=C2C(N=C(SCCN3CCOCC3)N2)=C1.Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : 100 mg/mL (290.81 mM; Need ultrasonic)

DMSO : ≥ 44 mg/mL (127.96 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.9081 mL 14.5404 mL 29.0808 mL
5 mM 0.5816 mL 2.9081 mL 5.8162 mL
10 mM 0.2908 mL 1.4540 mL 2.9081 mL
*Please refer to the solubility information to select the appropriate solvent.
References
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This equation is commonly abbreviated as: C1V1 = C2V2

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Product Name:
Fabomotizole hydrochloride
Cat. No.:
HY-14895A
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