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Fabomotizole (Synonyms: CM346)

Cat. No.: HY-14895
Handling Instructions

Fabomotizole is an anxiolytic drug; produces anxiolytic and neuroprotective effects without any sedative or muscle relaxant actions.

For research use only. We do not sell to patients.

Fabomotizole Chemical Structure

Fabomotizole Chemical Structure

CAS No. : 173352-21-1

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Description

Fabomotizole (CM346) is an anxiolytic drug; produces anxiolytic and neuroprotective effects without any sedative or muscle relaxant actions. IC50 value: Target: anxiolytic agent Afobazole's mechanism of action remains poorly defined however, with GABAergic, NGF and BDNF release promoting, MT1 receptor antagonism, MT3 receptor antagonism, and sigma agonism suggested as potential mechanisms. Afobazole was shown to inhibit MAO-A reversibly and there might be also some involvement with serotonin receptors. Afobazole has found little clinical use outside of Russia and has not been evaluated by the FDA.

Molecular Weight

307.41

Formula

C₁₅H₂₁N₃O₂S

CAS No.
SMILES

CCOC1=CC=C2C(N=C(SCCN3CCOCC3)N2)=C1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

FabomotizoleCM346CM 346CM-346OthersInhibitorinhibitorinhibit

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Fabomotizole
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