IRAK inhibitor 4 (trans)

Art. -Nr.: HY-13278A Reinheit: 99.02%: Data Sheet
COA

SDS
Handling Instructions
FAQs
Technical Support

IRAK inhibitor 4 (trans) is the trans form of IRAK inhibitor 4. IRAK inhibitor 4 is an interleukin-1 receptor associated kinase 4 (IRAK4) inhibitor.

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IRAK inhibitor 4 (trans) Chemische Struktur

CAS. Nr. : 2070014-89-8

Größe	Verfügbarkeit	Menge
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	Auf Lager	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	Auf Lager	Estimated Time of Arrival: December 31
Solid
2 mg	Auf Lager	Estimated Time of Arrival: December 31
5 mg	Auf Lager	Estimated Time of Arrival: December 31
10 mg	Auf Lager	Estimated Time of Arrival: December 31
25 mg	Auf Lager	Estimated Time of Arrival: December 31
50 mg	Auf Lager	Estimated Time of Arrival: December 31
100 mg	Auf Lager	Estimated Time of Arrival: December 31
200 mg	Angebot einholen
500 mg	Angebot einholen

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Other Forms of IRAK inhibitor 4 (trans):

IRAK inhibitor 4 In-stock

Spezialitätsempfehlungen

•Related Screening Libraries:

•Related Small Molecules:

•Related Proteins:

Alle IRAK Isoform-spezifische Produkte anzeigen:

Alle Isoformen anzeigen

IRAK1 IRAK3 IRAK4

Biologische Aktivität
Reinheit & Dokumentation
Verweise
Kundenbewertung

Beschreibung

IRAK inhibitor 4 (trans) is the trans form of IRAK inhibitor 4. IRAK inhibitor 4 is an interleukin-1 receptor associated kinase 4 (IRAK4) inhibitor.

IC₅₀ & Target

IRAK4

Molekulargewicht

620.66

Formel

C₃₃H₃₅F₃N₆O₃

CAS. Nr.

2070014-89-8

Appearance

Solid

Color

Light yellow to yellow

SMILES

O=C(C1=CC=C2C(N=C(NC3=NNC4=C3C=C(C5=CC=CC=C5OC(F)(F)F)C=C4)N2[C@@H]6CC[C@@H](O)CC6)=C1)NCCC(C)C

Versand

Room temperature in continental US; may vary elsewhere.

Speicherung

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	2 years
	-20°C	1 year

Lösungsmittel & Löslichkeit

In Vitro:

DMSO : ≥ 38 mg/mL (61.23 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.6112 mL	8.0559 mL	16.1119 mL
5 mM	0.3222 mL	1.6112 mL	3.2224 mL
10 mM	0.1611 mL	0.8056 mL	1.6112 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

Molaritätsrechner
Verdünnungsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

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Dosage

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Calculation results:

Working solution concentration: mg/mL

Reinheit & Dokumentation

Purity: 99.02%

Select Batch:

Data Sheet (272 KB) SDS (251 KB)

COA (252 KB) LCMS (268 KB)

Handling Instructions (2659 KB)

Verweise

[1]. Indazole derivatives as modulators of interleukin-1 receptor-associated kinase. Patent WO 2008030584 A2.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	1.6112 mL	8.0559 mL	16.1119 mL	40.2797 mL
	5 mM	0.3222 mL	1.6112 mL	3.2224 mL	8.0559 mL
	10 mM	0.1611 mL	0.8056 mL	1.6112 mL	4.0280 mL
	15 mM	0.1074 mL	0.5371 mL	1.0741 mL	2.6853 mL
	20 mM	0.0806 mL	0.4028 mL	0.8056 mL	2.0140 mL
	25 mM	0.0644 mL	0.3222 mL	0.6445 mL	1.6112 mL
	30 mM	0.0537 mL	0.2685 mL	0.5371 mL	1.3427 mL
	40 mM	0.0403 mL	0.2014 mL	0.4028 mL	1.0070 mL
	50 mM	0.0322 mL	0.1611 mL	0.3222 mL	0.8056 mL
	60 mM	0.0269 mL	0.1343 mL	0.2685 mL	0.6713 mL