1. JAK/STAT Signaling
    Protein Tyrosine Kinase/RTK
  2. EGFR

Lavendustin A (Synonyms: RG-14355)

Cat. No.: HY-18963
Handling Instructions

Lavendustin A (RG-14355), isolated from Streptomyces Griseolavendus, is a potent, specific and ATP-competitive inhibitor of tyrosine kinase, with an IC50 of 11 ng/mL for EGFR-associated tyrosine kinase. It suppresses VEGF-induced angiogenesis and blocks the induction of LTPGABA-A.

For research use only. We do not sell to patients.

Lavendustin A Chemical Structure

Lavendustin A Chemical Structure

CAS No. : 125697-92-9

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  • Biological Activity

  • Technical Information

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  • References

Description

Lavendustin A (RG-14355), isolated from Streptomyces Griseolavendus, is a potent, specific and ATP-competitive inhibitor of tyrosine kinase, with an IC50 of 11 ng/mL for EGFR-associated tyrosine kinase[1]. It suppresses VEGF-induced angiogenesis and blocks the induction of LTPGABA-A[2][3].

IC50 & Target

IC50: 11 ng/mL (EGFR-associated tyrosine kinase)[1].

References
Molecular Weight

381.38

Formula

C₂₁H₁₉NO₆

CAS No.

125697-92-9

SMILES

O=C(O)C1=CC(N(CC2=CC(O)=CC=C2O)CC3=CC=CC=C3O)=CC=C1O

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Shipping

Room temperature in continental US; may vary elsewhere

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Product Name:
Lavendustin A
Cat. No.:
HY-18963
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Lavendustin A

Cat. No.: HY-18963