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Monoammonium glycyrrhizinate hydrate 

Cat. No.: HY-76225
Handling Instructions

Monoammonium glycyrrhizinate hydrate has various pharmacological actions such as anti-inflammatory, antiallergic, antigastriculcer, and antihepatitis activities.

For research use only. We do not sell to patients.

Monoammonium glycyrrhizinate hydrate Chemical Structure

Monoammonium glycyrrhizinate hydrate Chemical Structure

CAS No. : 53956-04-0

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 55 In-stock
Estimated Time of Arrival: December 31
1 g USD 50 In-stock
Estimated Time of Arrival: December 31
5 g   Get quote  
10 g   Get quote  

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Customer Review

Other Forms of Monoammonium glycyrrhizinate hydrate:

  • Biological Activity

  • Technical Information

  • Purity & Documentation

  • References

Description

Monoammonium glycyrrhizinate hydrate has various pharmacological actions such as anti-inflammatory, antiallergic, antigastriculcer, and antihepatitis activities. In Vivo: The increase of the lung W/D weight ratios is significantly reduced by high and medium dose of MAG (10 and 30mg/kg) administration. Pretreatment with MAG (10 and 30mg/kg) efficiently reduces the production of TNF-𝛼 and IL-1𝛽. MAG (10, 30mg/kg) significantly decreases NF-𝜅B p65 protein expression, compared with LPS. On the contrary, LPS significantly reduces I𝜅B-𝛼 protein expression compared with the control group, whereas MAG (10 and 30mg/kg) significantly increased I𝜅B-𝛼 expression, compared with the LPS group[1].
Low- and high-dose MAG treatment significantly reduces the AST, ALT, TBIL, and TBA levels at 14 and 21 d time points when compared with that of the RIF and INH group, suggesting the protective effect of MAG on RIF- and INH-induced liver injury. MAG treatment groups elevate the hepatic GSH level at 7, 14, and 21 d time points and markedly reduce the MDA level at 14 and 21 d time points in RIF- and INH-treated rats, suggesting the protective effect of MAG in RIF- and INH induced liver injuries[2].

Solvent & Solubility
Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.1905 mL 5.9527 mL 11.9053 mL
5 mM 0.2381 mL 1.1905 mL 2.3811 mL
10 mM 0.1191 mL 0.5953 mL 1.1905 mL
*Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

839.96

Formula

C₄₂H₆₅NO₁₆

CAS No.

53956-04-0

SMILES

O=C1[[email protected]]([[email protected]](CC2)(C)[[email protected]@]3(C)C([[email protected]]([[email protected]@]4(C)CC3)([H])C[[email protected]@](CC4)(C)C(O)=O)=C1)([H])[[email protected]](CC5)(C)C2C([[email protected]]5O[[email protected]@H](O[[email protected]](C([O-])=O)[[email protected]]6O)[[email protected]](O[[email protected]@H]([[email protected]](O)[[email protected]@H](O)[[email protected]@H]7O)O[[email protected]@H]7C(O)=O)[[email protected]]6O)(C)C.[NH4+]

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Shipping

Room temperature in continental US; may vary elsewhere

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Product Name:
Monoammonium glycyrrhizinate hydrate
Cat. No.:
HY-76225
Quantity:

Monoammonium glycyrrhizinate hydrate

Cat. No.: HY-76225