1. Terpenoids and Glycosides
  2. Monoammonium glycyrrhizinate hydrate

Monoammonium glycyrrhizinate hydrate 

Cat. No.: HY-76225 Purity: 97.05%
Handling Instructions

Monoammonium glycyrrhizinate hydrate has various pharmacological actions such as anti-inflammatory, antiallergic, antigastriculcer, and antihepatitis activities.

For research use only. We do not sell to patients.

Monoammonium glycyrrhizinate hydrate Chemical Structure

Monoammonium glycyrrhizinate hydrate Chemical Structure

CAS No. : 53956-04-0

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10 mM * 1 mL in DMSO USD 55 In-stock
Estimated Time of Arrival: December 31
1 g USD 50 In-stock
Estimated Time of Arrival: December 31
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Based on 1 publication(s) in Google Scholar

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Description

Monoammonium glycyrrhizinate hydrate has various pharmacological actions such as anti-inflammatory, antiallergic, antigastriculcer, and antihepatitis activities. In Vivo: The increase of the lung W/D weight ratios is significantly reduced by high and medium dose of MAG (10 and 30mg/kg) administration. Pretreatment with MAG (10 and 30mg/kg) efficiently reduces the production of TNF-𝛼 and IL-1𝛽. MAG (10, 30mg/kg) significantly decreases NF-𝜅B p65 protein expression, compared with LPS. On the contrary, LPS significantly reduces I𝜅B-𝛼 protein expression compared with the control group, whereas MAG (10 and 30mg/kg) significantly increased I𝜅B-𝛼 expression, compared with the LPS group[1].
Low- and high-dose MAG treatment significantly reduces the AST, ALT, TBIL, and TBA levels at 14 and 21 d time points when compared with that of the RIF and INH group, suggesting the protective effect of MAG on RIF- and INH-induced liver injury. MAG treatment groups elevate the hepatic GSH level at 7, 14, and 21 d time points and markedly reduce the MDA level at 14 and 21 d time points in RIF- and INH-treated rats, suggesting the protective effect of MAG in RIF- and INH induced liver injuries[2].

Molecular Weight

839.96

Formula

C₄₂H₆₅NO₁₆

CAS No.

53956-04-0

SMILES
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Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Product Name:
Monoammonium glycyrrhizinate hydrate
Cat. No.:
HY-76225
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