Dipotassium glycyrrhizinate (Synonyms: Glycyrrhizic acid dipotassium; Dipotassium glycyrrhizate)

Cat. No.: HY-N0184A Purity: ≥98.0%: FAQs
Data Sheet SDS COA Handling Instructions

Dipotassium glycyrrhizinate is a natural compound, inhibits atopic dermatitis-related gene expression with anti-anti-inflammatory activity.

For research use only. We do not sell to patients.

Dipotassium glycyrrhizinate Chemical Structure

CAS No. : 68797-35-3

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Free Sample (0.1 - 0.5 mg)		Apply Now
Solution
10 mM * 1 mL in Water	USD 73	In-stock	Estimated Time of Arrival: December 31
Solid + Solvent
10 mM * 1 mL ready for reconstitution	USD 73	In-stock	Estimated Time of Arrival: December 31
Solid
50 mg	USD 66	In-stock	Estimated Time of Arrival: December 31
100 mg	USD 92	In-stock	Estimated Time of Arrival: December 31
200 mg	USD 132	In-stock	Estimated Time of Arrival: December 31
500 mg		Get quote
1 g		Get quote

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Based on 16 publication(s) in Google Scholar

Other Forms of Dipotassium glycyrrhizinate:

Ammonium glycyrrhizinate In-stock
Glycyrrhizic acid In-stock

15 Publications Citing Use of MCE Dipotassium glycyrrhizinate

: Dipotassium glycyrrhizinate purchased from MCE. Usage Cited in: Cell Prolif. 2020 Jun;53(6):e12829. [Abstract]; Protein levels of pro-caspase-1 + p10 + p12, GADMD, IL-1β, IL-18 and NLRP3 are detected by Western blotting. Glycyrrhizin inhibits pyroptosis in TNF-α-induced M1 macrophages.

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Description

Dipotassium glycyrrhizinate is a natural compound, inhibits atopic dermatitis-related gene expression with anti-anti-inflammatory activity^[1].

Clinical Trial

Molecular Weight

899.11

Appearance

Solid

Formula

C₄₂H₆₀K₂O₁₆

CAS No.

68797-35-3

SMILES

C[[email protected]]12[[email protected]@](C(C=C3[[email protected]]2(CC[[email protected]]4(C)[[email protected]@]3([H])C[[email protected]](C(O[K])=O)(C)CC4)C)=O)([H])[[email protected]@]5([[email protected]@](C(C)([[email protected]@H](O[[email protected]]6([H])[[email protected]@H]([[email protected]]([[email protected]](O)[[email protected]@H](C(O)=O)O6)O)O[[email protected]]7([H])O[[email protected]@H]([[email protected]@H](O)[[email protected]](O)[[email protected]]7O)C(O[K])=O)CC5)C)([H])CC1)C

Structure Classification

Source

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

H₂O : 50 mg/mL (55.61 mM; Need ultrasonic)

DMSO : 5 mg/mL (5.56 mM; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.1122 mL	5.5611 mL	11.1221 mL
5 mM	0.2224 mL	1.1122 mL	2.2244 mL
10 mM	0.1112 mL	0.5561 mL	1.1122 mL

*Please refer to the solubility information to select the appropriate solvent.

In Vivo:

1.

Add each solvent one by one: PBS
Solubility: 100 mg/mL (111.22 mM); Clear solution; Need ultrasonic

*All of the co-solvents are available by MCE.

Purity & Documentation

Purity: ≥98.0%

Select Batch:

Data Sheet (276 KB) SDS (252 KB)

COA (256 KB) HNMR (306 KB)

Handling Instructions (2659 KB)

References

[1]. Lee SH, et al. Ameliorating effect of dipotassium glycyrrhizinate on an IL-4- and IL-13-induced atopic dermatitis-like skin-equivalent model. Arch Dermatol Res. 2019 Mar;311(2):131-140. [Content Brief]

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Keywords:

Dipotassium glycyrrhizinate68797-35-3Glycyrrhizic acid dipotassium Dipotassium glycyrrhizateVirus ProteaseInhibitorinhibitorinhibit

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Dipotassium glycyrrhizinate (Synonyms: Glycyrrhizic acid dipotassium; Dipotassium glycyrrhizate)

Customer Review

Other Forms of Dipotassium glycyrrhizinate:

15 Publications Citing Use of MCE Dipotassium glycyrrhizinate

Featured Recommendations

•Related Screening Libraries:

Biological Activity

Purity & Documentation

References

Customer Review

Molarity Calculator

Dilution Calculator

The molarity calculator equation

The dilution calculator equation

Keywords:

Your Recently Viewed Products:

Customer Review

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