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- Carphephorus corymbosus (Nutt.) Torr. & A.Gray
Carphephorus corymbosus (Nutt.) Torr. & A.Gray
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Carphephorus corymbosus (Nutt.) Torr. & A.Gray (40)
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- Formula: C30H48O4
- Molecular Weight: 472.70
Saikogenin D is isolated from?Bupleurum chinense, has anti-inflammatory effects. Saikogenin D activates epoxygenases that converts arachidonic acid to epoxyeicosanoids and dihydroxyeicosatrienoic acids, and the metabolites secondarily inhibit prostaglandin E2 (PGE2) production. Saikogenin D results in an elevation of [Ca2+]i due to Ca2+ release from intracellular stores.
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- Formula: C48H78O17
- Molecular Weight: 927.12
Saikosaponin H is a saikosaponin derived from the herb Radix bupleuri.
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- Formula: C44H70O14
- Molecular Weight: 823.02
6''-O-Acetylsaikosaponin A, an acetyl saikosaponin isolated from the roots of Bupleurum chinense, shows some osteoclast-inhibiting activities.
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- Formula: C27H32O12
- Molecular Weight: 548.54
Maohuoside A, a single compound isolated from the E. koreanum that potently promotes osteogenesis. Maohuoside A enhances the osteogenesis of bone marrow-derived mesenchymal stem cells via bone morphogenetic protein (BMP) and MAPK signaling pathways.
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- Formula: C43H72O14
- Molecular Weight: 813.02
Saikosaponin B3 is a saikosaponin isolated from the roots of Bupleurum falcatum L., with analgesic effect. Saikosaponin B3 inhibits ACTH-induced lipolysis in the fat cells.
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- Formula: C42H68O13
- Molecular Weight: 780.98
Saikosaponin G is a triterpene glycoside isolated from Bupleurum chinensis.
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- Formula: C42H68O13
- Molecular Weight: 780.98
Saikosaponin B2 (Standard) is the analytical standard of Saikosaponin B2. This product is intended for research and analytical applications. Saikosaponin B2 is an antiviral and anticancer agent that regulates multiple transporters (such as various solute carriers and ATP-binding cassette transporters including MRP1, MRP2, and OCT2). Saikosaponin B2 is isolated from the plant glycoside component of the roots of Bupleurum scorzonerifolium. Saikosaponin B2 enhances the liver targeting of anticancer drugs via vinegar-baked Radix Bupleuri. Saikosaponin B2 inhibits HCV entry, replication, and translation, is effective against Daclatasvir (HY-10466)-resistant strains, and exerts a synergistic effect when used in combination with Daclatasvir. Saikosaponin B2 is commonly used in studies related to hepatocellular carcinoma and HCV infection.
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- Formula: C42H68O13
- Molecular Weight: 780.98
Saikosaponin B1 (Standard) is the analytical standard of Saikosaponin B1. This product is intended for research and analytical applications. Saikosaponin B1 is a bioactive constituent of Radix Bupleuri. Saikosaponin B1 is an agonist of the 5-HT2C receptor with an EC50 of 147.41 μM. Saikosaponin B1 inhibits the Hedgehog (Hh) signaling pathway by targeting the transmembrane protein SMO. Sailosaponin B1 can reduce liver fibrosis. Saikosaponin B1 has anti-cancer activities thus can be studies in research for cancers such as Medulloblastoma (MB).
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- Formula: C42H68O13
- Molecular Weight: 780.98
Saikosaponin A (Standard) is the analytical standard of Saikosaponin A. This product is intended for research and analytical applications. Saikosaponin A is the main active ingredient in Bupleurum chinense, which can regulate lipid metabolism and promote cholesterol efflux in early atherosclerosis. In addition, Saikosaponin A may also act as a potential peroxisome proliferator-activated receptor-γ (PPAR-γ) agonist, significantly promoting the expression of PPAR-γ. Saikosaponin A can be used in the study of hyperlipidemic pancreatitis.
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- Formula: C17H26O10
- Molecular Weight: 390.38
Reptoside, an iridoid glucoside, is a DNA damaging active agent. Reptoside has strong interactions with Trp352 and Tyr335 in AKT1.
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- Formula: C48H78O18
- Molecular Weight: 943.12
Saikosaponin S is a natural product that can be isolated from Bupleurum scorzonerifolium.
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- Formula: C48H78O18
- Molecular Weight: 943.12
Chikusaikoside Ⅱ is a natural product that can be isolated from Bupleurum longeradiatum.
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- Formula: C42H70O14
- Molecular Weight: 799.00
Bupleuroside XIII is a natural hepatoprotective saponin.
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- Formula: C16H14O7
- Molecular Weight: 318.28
Padmatin is a dihydroflavonol isolated from the heartwood of Prunus puddum.
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- Formula: C49H82O18
- Molecular Weight: 959.16
11(α)-Methoxysaikosaponin F is a triterpenoid saponin isolated from Bupleurum marginatum Wall.ex DC(ZYCH) which is a promising therapeutic for liver fibrosis. 11(α)-Methoxysaikosaponin F has an IC50 of 387.7 nM with viability of hepatic stellate cells-T6 (HSCs-T6). Triterpenoid saponins have numerous targets, important network positions, and strong inhibitory activity.
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- Formula: C10H11NO3
- Molecular Weight: 193.20
Ferulamide is a Ferulic acid derivative isolated from Portulaca oleracea L. with anticholinesterase activities.
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- Formula: C15H10O4
- Molecular Weight: 254.24
7,8-Dihydroxyflavone is a potent and selective TrkB agonist that mimics the physiological actions of Brain-derived neurotrophic factor (BDNF). Displays therapeutic efficacy toward various neurological diseases.
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- Formula: C32H52O2
- Molecular Weight: 468.75
Lupeol acetate (Standard) is the analytical standard of Lupeol acetate. This product is intended for research and analytical applications. Lupeol acetate is a derivative of Lupeol. Lupeol acetate is an anti-inflammatory, antibacterial, anti-trypanosomic and anticancer agent with oral activity. Lupeol acetate significantly improves the symptoms of rheumatoid arthritis by down-regulating the expression of inflammatory cytokines and osteoclast production. Lupeol acetate inhibits spermatogenesis in male rats and eventually led to infertility.
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