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- Salvia hypargeia Fisch. & C.A.Mey.
Salvia hypargeia Fisch. & C.A.Mey.
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Salvia hypargeia Fisch. & C.A.Mey. (14)
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- Formula: C24H28O7
- Molecular Weight: 428.47
Praeruptorin E is an orally active pyranocoumarin compound. Praeruptorin E can be isolated from the dried roots of Peucedanum praeruptorum Dunn. Praeruptorin E reduces the expression of NF-κB. Praeruptorin E upregulates the expression of PXR and CYP3A4. Praeruptorin E inhibits Th2 cytokines, TNF-α, IL6, MPO, and blocks the Ca2+ slow channel. Praeruptorin E promotes pulmonary tissue repair and relaxes porcine coronary artery strips. Praeruptorin E protects mice from lipopolysaccharide- and hydrochloric acid-induced acute lung injury. Praeruptorin E can be used in studies related to asthma and acute lung injury.
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- Formula: C21H22O7
- Molecular Weight: 386.40
Praeruptorin A ((+)-Praeruptorin A) is an orally active isomer of (±)-Praeruptorin A (HY-N0081). Praeruptorin A also acts as a Calcium channel blocker. Praeruptorin A can be isolated from Peucedanum. Praeruptorin A serves as a substrate for CYP3A4. Praeruptorin A downregulates NMDA receptors containing GluN2B and inhibits neuronal Apoptosis. Praeruptorin A mediates vasodilation, inhibits vascular hypertrophy and reduces blood pressure. Praeruptorin A can be used in research related to neurological diseases, myocardial ischemia, heart failure, exertional angina, renovascular hypertension and spontaneous hypertension.
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- Formula: C24H26O7
- Molecular Weight: 426.46
Praeruptorin B is an inhibitor of sterol regulatory element-binding proteins (SREBPs).
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- Formula: C14H16O5
- Molecular Weight: 264.27
(+)-Peusedanol is a coumarin isolated from Peucedanumjaponicum.
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- Formula: C22H30O7
- Molecular Weight: 406.47
Amarolide 11-acetate is a quassinoid, can be found in the barks of Ailanthus altissima.Amarolide 11-acetate exhibits nearly inactive cytotoxicity against human hepatoma cells.
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- Formula: C20H24O6
- Molecular Weight: 360.40
Molephantinin is a sesquiterpene lactone antitumor inhibitor that can be isolated from Elephantopus mollis H.S.K. Molephantinin inhibits the growth of Walker 256 carcinosarcoma and is used in studies related to Walker 256 carcinosarcoma.
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- Formula: C24H26O7
- Molecular Weight: 426.46
Praeruptorin B (Standard) is the analytical standard of Praeruptorin B. This product is intended for research and analytical applications. Praeruptorin B is an inhibitor of sterol regulatory element-binding proteins (SREBPs).
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- Formula: C19H22O6
- Molecular Weight: 346.37
Molephantin is a blood-brain barrier permeable anti-glioblastoma compound. Molephantin induces ROS generation, leading to mitochondrial damage, Mitophagy flux blockage and Apoptosis induction. Molephantin can suppress the PI3K/Akt/mTOR signaling pathway. Molephantin demonstrates antitumor effects against glioblastoma.
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- Formula: C21H26O6
- Molecular Weight: 374.43
2β-Methoxy-2-deethoxy-8-O-deacylphantomolin-8-O-tiglinate is a sesquiterpene lactone that can be isolated from Elephantopus mollis. 2β-Methoxy-2-deethoxy-8-O-deacylphantomolin-8-O-tiglinate exhibits cytotoxicity in mouse neuroblastoma B104 cells with an IC50 of 3.85 μM.
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- Formula: C24H28O7
- Molecular Weight: 428.47
Praeruptorin E (Standard) is the analytical standard of Praeruptorin E. This product is intended for research and analytical applications. Praeruptorin E is a main bioactive constituent of Peucedanum praeruptorum (also known as Bai-Hua Qian Hu). Praeruptorin C is a calcium antagonist with pD2′ value of 5.2.
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- Formula: C21H22O7
- Molecular Weight: 386.40
Praeruptorin A (Standard) is the analytical standard of Praeruptorin A. This product is intended for research and analytical applications. Praeruptorin A is a main bioactive constituent of Peucedanum praeruptorum (also known as Bai-Hua Qian Hu). Praeruptorin A exerts anti-inflammatory effects in vitro through inhibition of NF-κB activation.
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- Formula: C14H16O5
- Molecular Weight: 264.27
(+)-Peusedanol (Standard) is the analytical standard of (+)-Peusedanol. This product is intended for research and analytical applications. (+)-Peusedanol is a coumarin isolated from Peucedanumjaponicum.
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- Formula: C24H26O7
- Molecular Weight: 426.46
(-)-Anomalin (Standard) is the analytical standard of (-)-Anomalin. This product is intended for research and analytical applications. (-)-Anomalin ((-)-Praeruptorin B) is a coumarin derivative isolated from the root of Angelica anomala.
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