Infection
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Infection Related Products (18789)
Related Products (18789)
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Antibodies (22)
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SARS-CoV-2-IN-122
0 ImagesCat. No.: HY-182913SARS-CoV-2-IN-122 is a SARS-CoV-2 inhibitor by targeting the S2 subunit of the spike protein. SARS-CoV-2-IN-122 interacts with residues linked to membrane fusion-associated conformational rearrangements, interfering with viral entry events. SARS-CoV-2-IN-122 inhibits SARS-CoV-2 replication, lacks direct virucidal activity, and does not impair viral-host cell attachment. SARS-CoV-2-IN-122 exhibits activity against SARS-CoV-2 variants including B.1 and Omicron (BA.2.86.1). SARS-CoV-2-IN-122 can be used for the research of coronavirus disease 2019 (COVID-19).
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Moroxydine (hydrochloride)-d8
0 ImagesCat. No.: HY-W713297CAS No.: 2469734-82-3Synonyms: ABOB hydrochloride-d8Moroxydine hydrochloride-d8 (ABOB hydrochloride-d8) is the deuterium labeled Moroxydine (ABOB) hydrochloride (HY-B0420A). Moroxydine hydrochloride is a broad-spectrum agent with multi-antiviral activities against DNA and RNA viruses, including influenza virus, herpes simplex, varicella zoster, measles, mumps disease, hepatitis C virus, etc. Moroxydine hydrochloride exhibits excellent antiviral activity and shows low cytotoxicity to cells infected by dsRNA viruses (grass carp reovirus, GCRV) and large DNA viruses (giant salamander iridovirus, GSIV). Moroxydine hydrochloride blocks the GCRV-induced cytopathic effects and eliminates nucleocapsids in ctenopharyngodon idella kidney (CIK) cells to keep the normal morphological structure. Moroxydine hydrochloride significantly inhibits the apoptosis, the caspase 3 activity, Bax expression and down-regulates Bcl-2 levels[1][2][3].
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MtUng-IN-1
0 ImagesCat. No.: HY-149349CAS No.: 359826-99-6MtUng-IN-1 (Compound 18a) is a Uracil DNA glycosylase of Mycobacterium (MtUng) inhibitor (IC50: 300 μM). MtUng-IN-1 can be used for research of cancers and infectious diseases.
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Valomaciclovir stearate
0 ImagesCat. No.: HY-19288CAS No.: 195156-77-5Synonyms: ABT 606; MIV 606; A 174606.0Valomaciclovir stearate (ABT 606), a nucleoside analog, is the Omaciclovir (HY-116174) prodrug. Valomaciclovir stearate has antiviral activity against HSV-1 and varicella zoster virus (VZV).
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Vertixanthone
0 ImagesCat. No.: HY-N19119CAS No.: 120461-93-0Vertixanthone is an antifungal agent, with MIC values of 3.125 μg/mL against Candida albicans CMCC 98001 and 12.5 μg/mL against Aspergillus niger R330. Vertixanthone can be used for the research of candida albicans infection, aspergillus niger infection.
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Antimalarial agent 51
0 ImagesCat. No.: HY-176223Antimalarial agent 51 (Compound 2) is an orally active antimalarial compound. Antimalarial agent 51 blocks nutrient uptake by Plasmodium by inhibiting the plasmodium surface anion channel (PSAC). Antimalarial agent 51 significantly inhibits the growth of Plasmodium under nutrient-restricted conditions. Combination of antimalarial agent 51 with the residual transport inhibitor PRT-2 can enhance the antimalarial effect. Antimalarial agent 51 can be used in the study of malaria targeting the PSAC channel.
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Lupulone (Standard)
0 ImagesCat. No.: HY-124923RCAS No.: 468-28-0Lupulone (Standard) is the analytical standard of Lupulone. This product is intended for research and analytical applications. Lupulone is a beta-acid from the hop plant H. lupulus with diverse biological activities including antibacterial, antioxidant, and anticarcinogenic properties.
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HRSV/HMPV-IN-1
0 ImagesCat. No.: HY-169313CAS No.: 2994287-06-6HRSV/HMPV-IN-1 (compound 3) is a HRSV/HMPV inhibitor with the EC50 values of ＜ 0.2 μM and ＜ 0.5 μM for human RSV-A and human MPV A2 TN/94-49, respectively. HRSV/HMPV-IN-1 can be used for study of bronchiolitis and pneumonia.
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Guaiol (Standard)
0 ImagesGuaiol (Standard) is the analytical standard of Guaiol. This product is intended for research and analytical applications. Guaiol is a sesquiterpenoid alcohol with oral activity found in various traditional Chinese medicines, exhibiting biological activities such as anti-proliferative, autophagy-promoting, insecticidal, anti-anxiety, anti-inflammatory, diuretic, and blood pressure-lowering effects. Guaiol induces apoptosis in non-small cell lung cancer cells by regulating the stability of RAD51 through autophagy modulation. Guaiol can also act directly on parasites, inhibiting their growth by affecting the kinetoplast, mitochondrial matrix and plasma membrane of the promastigotes. Guaiol kills amastigotes at an IC50 of 0.01 µg/mL. Guaiol can be used in research related to cancer, infections, cardiovascular diseases, and inflammatory conditions[4]
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Fleroxacin-d3
0 ImagesCat. No.: HY-B0414SSynonyms: RO 23-6240-d3; AM-833-d3Fleroxacin-d3 (RO 23-6240-d3) is the deuterium labeled Fleroxacin (HY-B0414). Fleroxacin (RO 23-6240) is a broad-spectrum antimicrobial fluoroquinolone.
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A88696C
0 ImagesCat. No.: HY-N19130CAS No.: 155520-96-0A88696C is a gastric H+/K+ ATP-ase inhibitor with a pig IC50 of 59 μM. A88696C inhibits gastric ATP-ase activity.
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Varacin
0 ImagesCat. No.: HY-N21817CAS No.: 134029-48-4Varacin is a benzopentathiepin polysulfide derived from marine ascidians. It exerts cytotoxic, antibacterial, and antifungal activities by cleaving DNA through a redox pathway. Varacin can be used in research on cancer, fungal infections, and bacterial infections.
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Antibacterial agent 188
0 ImagesCat. No.: HY-162296CAS No.: 88312-54-3Antibacterial agent 188 (compound 2d) is an antibacterial agent that inhibits dermatophyte activity.
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SARS-CoV-2 Mpro-IN-45
0 ImagesCat. No.: HY-176211CAS No.: 2992608-40-7
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Micronomicin (Standard)
0 ImagesSynonyms: Gentamicin C2b (Standard); Antibiotic XK-62-2 (Standard); Sagamicin (Standard)Micronomicin (Standard) is the analytical standard of Micronomicin. This product is intended for research and analytical applications. Micronomicin (Gentamicin C2b) is an aminoglycoside antibiotic, with antibacterial and bactericidal activities.
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Methotrexate diethyl ester
0 ImagesCat. No.: HY-Z15986CAS No.: 43170-88-3Methotrexate diethyl ester is a potent DHFR inhibitor. Methotrexate diethyl ester can be used in the research of T.cruzi infection and leukemia.
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DHFR-IN-27
0 ImagesCat. No.: HY-183286DHFR-IN-27 (Compound LA4) is an orally active DHFR inhibitor and antimalarial agent, with a Ki value of 1.71 nM against TgDHFR. DHFR-IN-27 reduces the parasitic load of Toxoplasma gondii in infected mice and prolongs the survival time of infected mice. DHFR-IN-27 exerts Antiparasitic effects against Toxoplasma gondii. DHFR-IN-27 can be used in the research of toxoplasmosis.
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SARS-CoV-2-IN-22
0 ImagesCat. No.: HY-146157CAS No.: 2710278-53-6SARS-CoV-2-IN-22 is a SARS-CoV-2 pseudovirus entry inhibitor with an IC50 value of 16.96 µM.
